{"id":302,"date":"2021-06-25T22:13:11","date_gmt":"2021-06-25T13:13:11","guid":{"rendered":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/?p=302"},"modified":"2024-10-20T03:04:53","modified_gmt":"2024-10-19T18:04:53","slug":"%e3%83%88%e3%83%aa%e3%83%97%e3%83%ab%e3%83%8d%e3%82%ac%e3%83%86%e3%82%a3%e3%83%96%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6-q-and-a","status":"publish","type":"post","link":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/approach\/%e3%83%88%e3%83%aa%e3%83%97%e3%83%ab%e3%83%8d%e3%82%ac%e3%83%86%e3%82%a3%e3%83%96%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6-q-and-a\/","title":{"rendered":"\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306b\u3064\u3044\u3066 Q and A"},"content":{"rendered":"

\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\uff08TNBC\uff09\u7279\u5fb4\u306b\u3064\u3044\u3066\u6559\u3048\u3066\u304f\u3060\u3055\u3044<\/h3>\n

1. \u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u6b20\u5982<\/strong><\/h4>\n

TNBC\u306f\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08ER\uff09<\/strong>\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53\uff08PR\uff09<\/strong>\u3001\u304a\u3088\u3073HER2\u30bf\u30f3\u30d1\u30af\u8cea<\/strong>\u306e\u3044\u305a\u308c\u3082\u767a\u73fe\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u300c\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3084HER2\u306b\u5bfe\u3059\u308b\u6a19\u7684\u7642\u6cd5\u304c\u52b9\u679c\u3092\u793a\u3055\u305a\u3001\u4ed6\u306e\u4e73\u764c\u30bf\u30a4\u30d7\u3068\u306f\u7570\u306a\u308b\u6cbb\u7642\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

2. \u9032\u884c\u306e\u901f\u3055<\/strong><\/h4>\n

TNBC\u306f\u4e00\u822c\u7684\u306b\u5897\u6b96\u304c\u65e9\u304f<\/strong>\u3001\u8a3a\u65ad\u6642\u306b\u306f\u9032\u884c\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u4ed6\u306e\u4e73\u764c\u306b\u6bd4\u3079\u3066\u60aa\u6027\u5ea6\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u65e9\u671f\u306b\u8ee2\u79fb\u3059\u308b\u30ea\u30b9\u30af\u304c\u3042\u308a\u3001\u518d\u767a\u7387\u3082\u6bd4\u8f03\u7684\u9ad8\u3044\u3067\u3059\u3002<\/p>\n

3. \u4e88\u5f8c\u306e\u53b3\u3057\u3055<\/strong><\/h4>\n

TNBC\u306f\u518d\u767a\u7387\u304c\u9ad8\u304f\u3001\u7279\u306b\u6cbb\u7642\u5f8c5\u5e74\u4ee5\u5185\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u4e73\u764c\u3088\u308a\u9ad8\u3044\u3067\u3059\u3002\u305f\u3060\u3057\u3001\u5316\u5b66\u7642\u6cd5\u306b\u306f\u6bd4\u8f03\u7684\u611f\u53d7\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u65e9\u671f\u767a\u898b\u3068\u9069\u5207\u306a\u6cbb\u7642\u306b\u3088\u308a\u4e88\u5f8c\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n

4. \u82e5\u5e74\u5973\u6027\u306b\u591a\u3044<\/strong><\/h4>\n

TNBC\u306f\u4ed6\u306e\u4e73\u764c\u306b\u6bd4\u3079\u3066\u3001\u82e5\u5e74\u5973\u6027\uff0840\u6b73\u4ee5\u4e0b\uff09\u306b\u767a\u75c7\u3057\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u30a2\u30d5\u30ea\u30ab\u7cfb\u3084\u30d2\u30b9\u30d1\u30cb\u30c3\u30af\u7cfb<\/strong>\u306e\u5973\u6027\u306b\u591a\u304f\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n

5. BRCA1\u907a\u4f1d\u5b50\u3068\u306e\u95a2\u9023<\/strong><\/h4>\n

TNBC\u306f\u3001\u7279\u306bBRCA1\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u3092\u6301\u3064\u60a3\u8005\u306b\u591a\u304f\u767a\u75c7\u3057\u307e\u3059\u3002\u3053\u306e\u5909\u7570\u3092\u6301\u3064\u5973\u6027\u306fTNBC\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u200b<\/p>\n

6. \u6cbb\u7642\u306e\u9078\u629e\u80a2<\/strong><\/h4>\n

TNBC\u306f\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3084HER2\u30bf\u30fc\u30b2\u30c3\u30c8\u7642\u6cd5\u304c\u4f7f\u3048\u306a\u3044\u305f\u3081\u3001\u4e3b\u306b\u5316\u5b66\u7642\u6cd5<\/strong>\u304c\u6cbb\u7642\u306e\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002\u8fd1\u5e74\u3067\u306f\u3001\u514d\u75ab\u7642\u6cd5\uff08\u30da\u30f3\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306a\u3069\uff09\u3084<\/strong>\u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09\u3068\u3044\u3063\u305f\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u9032\u884c\u671f\u3084\u518d\u767a\u30ea\u30b9\u30af\u306e\u9ad8\u3044TNBC\u306b\u5bfe\u3057\u3066\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u200b<\/p>\n

\u307e\u3068\u3081<\/h4>\n

\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\u306f\u3001\u7279\u5b9a\u306e\u53d7\u5bb9\u4f53\u306e\u6b20\u5982\u3084\u60aa\u6027\u5ea6\u306e\u9ad8\u3055\u3001\u82e5\u5e74\u5973\u6027\u3078\u306e\u767a\u75c7\u304c\u591a\u3044\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002\u6cbb\u7642\u306e\u9078\u629e\u80a2\u304c\u9650\u3089\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u7814\u7a76\u304c\u6d3b\u767a\u306b\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u3082\u4e88\u5f8c\u6539\u5584\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\u306e\u5468\u8853\u671f\uff08\u624b\u8853\u524d\u5f8c\u306e\uff09\u306e\u85ac\u7269\u7642\u6cd5\u306b\u3064\u3044\u3066\u6559\u3048\u3066\u304f\u3060\u3055\u3044<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n
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\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\uff08TNBC\uff09\u306e\u5468\u8853\u671f\uff08\u624b\u8853\u524d\u5f8c\uff09\u306e\u85ac\u7269\u7642\u6cd5\u306f\u3001\u4e3b\u306b\u5316\u5b66\u7642\u6cd5\u3068\u514d\u75ab\u7642\u6cd5\u304c\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u8fd1\u5e74\u3067\u306f\u65b0\u3057\u3044\u6cbb\u7642\u9078\u629e\u80a2\u3082\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u4e3b\u306a\u6cbb\u7642\u6cd5\u3092\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n

1. \u30cd\u30aa\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u7642\u6cd5\uff08\u624b\u8853\u524d\u306e\u6cbb\u7642\uff09<\/strong><\/h4>\n

\u624b\u8853\u524d\u306b\u884c\u308f\u308c\u308b\u5316\u5b66\u7642\u6cd5\u3084\u514d\u75ab\u7642\u6cd5\u3067\u3001\u816b\u760d\u3092\u7e2e\u5c0f\u3057\u624b\u8853\u306e\u6210\u529f\u7387\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u76ee\u7684\u3067\u3059\u3002<\/p>\n

    \n
  • \u5316\u5b66\u7642\u6cd5<\/strong>\uff1aTNBC\u3067\u306f\u3001\u4e00\u822c\u7684\u306b\u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u7cfb<\/strong>\u3084\u30bf\u30ad\u30b5\u30f3\u7cfb<\/strong>\u306e\u5316\u5b66\u7642\u6cd5\u304c\u6a19\u6e96\u6cbb\u7642\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u624b\u8853\u524d\u306b\u816b\u760d\u3092\u7e2e\u5c0f\u3055\u305b\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n
  • \u514d\u75ab\u7642\u6cd5<\/strong>\uff1a\u8fd1\u5e74\u3001\u30da\u30f3\u30d6\u30ed\u30ea\u30ba\u30de\u30d6<\/strong>\uff08\u6297PD-1\u6297\u4f53\uff09\u304c\u5316\u5b66\u7642\u6cd5\u3068\u4f75\u7528\u3055\u308c\u308b\u30b1\u30fc\u30b9\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002KEYNOTE-522\u8a66\u9a13\u306b\u3088\u308b\u3068\u3001\u30da\u30f3\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3092\u5316\u5b66\u7642\u6cd5\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u6cbb\u7642\u306f\u3001\u65e9\u671fTNBC\u306e\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\u7387\uff08\u816b\u760d\u306e\u6d88\u5931\u7387\uff09\u3092\u6539\u5584\u3057\u3001\u4e88\u5f8c\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u200b<\/li>\n<\/ul>\n

    \u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u7642\u6cd5\uff08\u624b\u8853\u5f8c\u306e\u6cbb\u7642\uff09<\/strong><\/h4>\n

    \u624b\u8853\u5f8c\u306b\u884c\u308f\u308c\u308b\u85ac\u7269\u7642\u6cd5\u306f\u3001\u518d\u767a\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u76ee\u7684\u3067\u5b9f\u65bd\u3055\u308c\u307e\u3059\u3002<\/p>\n

      \n
    • \u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u5316\u5b66\u7642\u6cd5<\/strong>\uff1a\u624b\u8853\u5f8c\u306e\u518d\u767a\u4e88\u9632\u306e\u305f\u3081\u306b\u3001\u5316\u5b66\u7642\u6cd5\u304c\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002\u7279\u306b\u518d\u767a\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u5834\u5408\u306b\u306f\u3001\u8907\u6570\u306e\u85ac\u5264\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/li>\n
    • \u514d\u75ab\u7642\u6cd5\u306e\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u4f7f\u7528<\/strong>\uff1a\u30da\u30f3\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306e\u3088\u3046\u306a\u514d\u75ab\u7642\u6cd5\u304c\u624b\u8853\u5f8c\u3082\u7d9a\u3051\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u306b\u3088\u3063\u3066\u514d\u75ab\u7cfb\u3092\u523a\u6fc0\u3057\u3001\u304c\u3093\u7d30\u80de\u306e\u518d\u767a\u3092\u9632\u3050\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u200b<\/li>\n<\/ul>\n

      3. \u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09<\/strong><\/h4>\n

      \u9032\u884c\u3057\u305fTNBC\u3084\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u306b\u306f\u3001\u30b5\u30b7\u30c4\u30ba\u30de\u30d6\u30fb\u30b4\u30d3\u30c6\u30ab\u30f3<\/strong>\u306e\u3088\u3046\u306a\u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09\u304c\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\uff08\u65e5\u672c\u672a\u627f\u8a8d\uff09\u3002\u3053\u306e\u85ac\u5264\u306f\u3001\u816b\u760d\u7d30\u80de\u3092\u7279\u7570\u7684\u306b\u653b\u6483\u3059\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u304f\u3001\u304b\u3064\u5f37\u529b\u306a\u6297\u816b\u760d\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u200b<\/p>\n

      \u6cbb\u7642\u306e\u9078\u629e\u80a2<\/h4>\n

      TNBC\u306e\u5468\u8853\u671f\u6cbb\u7642\u3067\u306f\u3001\u60a3\u8005\u306e\u816b\u760d\u306e\u7279\u5fb4\u3084\u500b\u5225\u306e\u30ea\u30b9\u30af\u8981\u56e0\u306b\u57fa\u3065\u3044\u3066\u3001\u6cbb\u7642\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002\u4eca\u5f8c\u306f\u3001\u816b\u760d\u6d78\u6f64\u30ea\u30f3\u30d1\u7403\uff08TILs\uff09\u306e\u3088\u3046\u306a\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u7528\u3044\u305f\u500b\u5225\u5316\u533b\u7642\u304c\u3055\u3089\u306b\u9032\u5c55\u3057\u3001\u3088\u308a\u9069\u5207\u306a\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u200b<\/p>\n

      \u3053\u308c\u3089\u306e\u6cbb\u7642\u6226\u7565\u306b\u3088\u308a\u3001TNBC\u60a3\u8005\u306e\u4e88\u5f8c\u304c\u6539\u5584\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u6cbb\u7642\u306e\u526f\u4f5c\u7528\u3084\u60a3\u8005\u3054\u3068\u306e\u53cd\u5fdc\u306b\u5fdc\u3058\u305f\u614e\u91cd\u306a\u6cbb\u7642\u8a08\u753b\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n

      —————————————————————————<\/p>\n

      Q:\u00a0\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09\u306e\u6700\u65b0\u306e\u8853\u524d\u30fb\u8853\u5f8c\u5316\u5b66\u7642\u6cd5\u306b\u3064\u3044\u3066\u6559\u3048\u3066\u304f\u3060\u3055\u3044<\/span><\/strong><\/h4>\n

      A:\u3000\u56fd\u969b\u7684\u306b\u6700\u3082\u53c2\u7167\u3055\u308c\u3066\u3044\u308b\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u4e00\u3064\u3067\u3042\u308bNCCN\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u3088\u308c\u3070\u3001HER2\u9670\u6027\u4e73\u304c\u3093\u306e\u671b\u307e\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u4ee5\u4e0b\u304c\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n

      \u25a0Dose-dense AC \u21922\u9031\u6bce\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb<\/p>\n

      \u25a0Dose-dense AC \u2192\u6bce\u9031\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb<\/p>\n

      \u25a0TC\uff08\u30c9\u30bb\u30bf\u30ad\u30bb\u30eb\uff0b\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\uff09<\/p>\n

      \u25a0\u3082\u3057germline BRCA1\/2<\/em>\u306b\u5909\u7570\u304c\u3042\u308c\u3070\u30aa\u30e9\u30d1\u30ea\u30d6\uff08\u65e5\u672c\u306f2022\u5e74\u79cb\u306b\u8a8d\u53ef\uff1f\uff09\u306e\u9069\u5fdc<\/p>\n

      \u25a0\u9ad8\u30ea\u30b9\u30af\u306eTNBC\u3000\u8853\u524d\u30ad\u30fc\u30c8\u30eb\u30fc\u30c0\uff0b\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\uff0b\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u2192\u8853\u524d\u30ad\u30fc\u30c8\u30eb\u30fc\u30c0\uff0bAC\uff08\u307e\u305f\u306fEC\uff09\u2192\u8853\u5f8c\u30ad\u30fc\u30c8\u30eb\u30fc\u30c0\uff08\u65e5\u672c\u306f2022\u5e74\u79cb\u306b\u8a8d\u53ef\uff1f\uff09<\/p>\n

      \u25a0TNBC\u3067\u8853\u524d\u7642\u6cd5ACT\u30d9\u30fc\u30b9\u306e\u5316\u5b66\u7642\u6cd5\u3067\u816b\u760d\u306e\u907a\u6b8b\u3042\u308a\u2192\u30bc\u30ed\u30fc\u30c0\u5185\u670d\u3092\u8ffd\u52a0<\/p>\n

      \u6bd4\u8f03\u7684\u4f4e\u30ea\u30b9\u30af\u306eTNBC\u306b\u306fTC\u7642\u6cd5\uff58\uff14\u30b5\u30a4\u30af\u30eb\u3001\u518d\u767a\u306e\u4e2d\u30ea\u30b9\u30af\u4ee5\u4e0a\u306eTNBC\u306b\u306fDose-dense AC \u2192\u6bce\u9031\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\uff082\u9031\u6bce\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\uff09\u304c\u73fe\u5728\u7528\u3044\u3089\u308c\u3066\u304a\u308a\u30012022\u5e74\u79cb\u4ee5\u964d\u306b\u30ad\u30fc\u30c8\u30eb\u30fc\u30c0\u3001\u30aa\u30e9\u30d1\u30ea\u30d6\u304c\u5468\u8853\u671f\u4e73\u304c\u3093\u306b\u627f\u8a8d\uff08\u4fdd\u967a\u9069\u5fdc\uff09\u3055\u308c\u308c\u3070\u3001\u3053\u308c\u3089\u304c\u6cbb\u7642\u306b\u7d44\u307f\u8fbc\u307e\u308c\u308b\u3053\u3068\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u73fe\u5728\uff082022\u5e744\u6708\uff09\u306b\u6cbb\u7642\u3092\u59cb\u3081\u305f\u65b9\u306b\u306f\u3001\u8853\u5f8c\u306e\u88dc\u52a9\u7642\u6cd5\u306e\u6bb5\u968e\u3067\u3001\u3053\u308c\u3089\u306e\u6cbb\u7642\u304c\u8ffd\u52a0\u3055\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

      Q:\u00a0\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09\u306e\u7279\u5fb4\u3001\u5171\u901a\u70b9\u306b\u3064\u3044\u3066\u6559\u3048\u3066\u304f\u3060\u3055\u3044<\/span><\/strong><\/h4>\n

      A:\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e3\u3064\u306e\u5171\u901a\u70b9\u306b\u3064\u3044\u3066<\/span><\/strong><\/p>\n

      \uff11\uff09\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306f\u3001\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u4e73\u304c\u3093\u306b\u6bd4\u3079\u3066\u9032\u884c\u304c\u901f\u304f\u3001\u4e88\u5f8c\u304c\u60aa\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3092\u6cbb\u7642\u3059\u308b\u6a19\u7684\u85ac\u304c\u5c11\u306a\u3044\u3053\u3068\u3082\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306f\u3001\u4e73\u623f\u4ee5\u5916\u306b\u3082\u5e83\u304c\u308a\u3084\u3059\u304f\u3001\u6cbb\u7642\u5f8c\u306b\u518d\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3053\u3068\u304c\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n

      \uff12\uff09\u307e\u305f\u3001\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u4e73\u304c\u3093\u3088\u308a\u3082\u60aa\u6027\u5ea6\uff08\u30b0\u30ec\u30fc\u30c9\uff09\u304c\u9ad8\u3044\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u30b0\u30ec\u30fc\u30c9\u304c\u9ad8\u3044\u307b\u3069\u3001\u304c\u3093\u7d30\u80de\u306e\u5916\u89b3\u3084\u5897\u6b96\u30d1\u30bf\u30fc\u30f3\u304c\u3001\u6b63\u5e38\u3067\u5065\u5eb7\u306a\u4e73\u817a\u7d30\u80de\u306b\u4f3c\u3066\u3044\u306a\u3044\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e\u30b0\u30ec\u30fc\u30c9\u306f\u3001\u591a\u304f\u306e\u5834\u5408\uff13\u6bb5\u968e\u306e\u3046\u3061\u306e\u30b0\u30ec\u30fc\u30c93\u3067\u3059\u3002<\/span><\/strong>
      \n\uff13\uff09\u307e\u305f\u3001”\u57fa\u5e95\u7d30\u80de\u69d8 “\u3068\u547c\u3070\u308c\u308b\u7d30\u80de\u30bf\u30a4\u30d7\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002”\u57fa\u5e95\u7d30\u80de\u69d8 “\u3068\u306f\u3001\u4e73\u7ba1\u306b\u4e26\u3076\u57fa\u5e95\u7d30\u80de\u306b\u4f3c\u305f\u7d30\u80de\u3067\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u57fa\u5e95\u7d30\u80de\u69d8\u4e73\u304c\u3093\u306f\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3068\u540c\u69d8\u306b\u3001\u3088\u308a\u653b\u6483\u7684\u3067\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u304c\u3093\u306b\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u57fa\u5e95\u7d30\u80de\u69d8\u4e73\u304c\u3093\u306e\u591a\u304f\u304c\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u3067\u3042\u308a\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e\u591a\u304f\u304c\u57fa\u5e95\u7d30\u80de\u69d8\u4e73\u304c\u3093\u3067\u3059\u3002<\/span><\/strong><\/p>\n

      \"\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\"

      \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093<\/p><\/div>\n

      Q: \u79c1\u306f\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09\u3068\u8a3a\u65ad\u3055\u308c\u30011\u4eba\u306e\u533b\u5e2b\u304b\u3089\u306f\u7528\u91cf\u306e\u591a\u3044\u5316\u5b66\u7642\u6cd5\u3092\u52e7\u3081\u3089\u308c\u3001\u3082\u30461\u4eba\u306e\u533b\u5e2b\u304b\u3089\u306fAC\u3068\u547c\u3070\u308c\u308b\u30ec\u30b8\u30e1\u30f3\u3067\u6cbb\u7642\u53ef\u80fd\u3068\u306e\u8aac\u660e\u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u3053\u306e\u305f\u3081\u5c11\u3057\u6df7\u4e71\u3057\u3066\u3044\u307e\u3059\u3002\u5148\u751f\u306e\u75c5\u9662\u3067\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u6cbb\u7642\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u304b\uff1f\u307e\u305f\u3001\u30b9\u30c6\u30fc\u30b8\u2161\u306e\u4e73\u304c\u3093\u306e\u6cbb\u7642\u306b\u7528\u91cf\u306e\u591a\u3044\u5316\u5b66\u7642\u6cd5\u306f\u6709\u52b9\u3067\u3057\u3087\u3046\u304b\uff1f<\/strong><\/span><\/h4>\n

      A: \u4e00\u822c\u7684\u306b\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09\u3068\u547c\u3070\u308c\u308bHER2\u9670\u6027\u3001ER\u9670\u6027\u3001PR\u9670\u6027\u306e\u4e73\u304c\u3093\u60a3\u8005\u3055\u3093\u306e\u5834\u5408\uff082021\u5e74\u73fe\u5728\uff09\u5316\u5b66\u7642\u6cd5\u304c\u5168\u8eab\u6cbb\u7642\u306e\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u30bf\u30a4\u30d7\u306e\u4e73\u304c\u3093\u306b\u5bfe\u3059\u308b\u7406\u89e3\u3092\u6df1\u3081\u3001\u3088\u308a\u30bf\u30fc\u30b2\u30c3\u30c8\u3092\u7d5e\u3063\u305f\u4ed6\u306e\u6cbb\u7642\u6cd5\u3092\u7814\u7a76\u3059\u308b\u3053\u3068\u306f\u3001\u3053\u306e\u5206\u91ce\u306e\u591a\u304f\u306e\u4eba\u3005\u306b\u3068\u3063\u3066\u6700\u512a\u5148\u4e8b\u9805\u3067\u3059\u3002\u30b9\u30c6\u30fc\u30b8\u2161\u306eTNBC\u60a3\u8005\u3067\u3001\u5fc3\u81d3\u3084\u305d\u306e\u4ed6\u306e\u6df1\u523b\u306a\u5065\u5eb7\u554f\u984c\u304c\u306a\u3044\u5834\u5408\u3001\u9ad8\u7528\u91cf\u8a2d\u5b9a\u3055\u308c\u305f\u30c9\u30ad\u30bd\u30eb\u30d3\u30b7\u30f3\/\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\uff082\u9031\u6bce\uff09\u306b\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u3092\u6295\u4e0e\u3059\u308b\u30ec\u30b8\u30e1\u30f3\u3001\u3059\u306a\u308f\u3061ddAC-T\u304c\u6a19\u6e96\u7684\u306a\u6cbb\u7642\u6cd5\u3067\u3059\u3002\u3042\u306a\u305f\u306e\u72b6\u6cc1\u3084\u9078\u629e\u80a2\u306b\u3064\u3044\u3066\u3001\u62c5\u5f53\u533b\u3068\u3088\u304f\u8a71\u3057\u5408\u3046\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/strong><\/span><\/p>\n

      Q: \u4ed6\u306e\u4e73\u304c\u3093\u3068\u3044\u308d\u3044\u308d\u306a\u9762\u3067\u9055\u3046\u3068\u4f3a\u3044\u307e\u3057\u305f\u3002\u4f55\u304b\u518d\u767a\u306e\u30d1\u30bf\u30fc\u30f3\u306b\u7279\u5fb4\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/strong><\/span><\/h4>\n

      \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306f\u3001\u72ec\u7279\u306e\u75c5\u7406\u5b66\u7684\u3001\u5206\u5b50\u751f\u7269\u5b66\u7684\u3001\u81e8\u5e8a\u7684\u306a\u7279\u5fb4\u3092\u6301\u3064\u4e73\u304c\u3093\u3067\u3059\u3002\u4eba\u7a2e\u306e\u9762\u3067\u306f\u82e5\u3044\u9ed2\u4eba\u5973\u6027\u306b\u591a\u304f\u767a\u75c7\u3057\u3001\u518d\u767a\u307e\u3067\u306e\u671f\u9593\u304c\u77ed\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8ee2\u79fb\u30fb\u518d\u767a\u306e\u90e8\u4f4d\u3068\u3057\u3066\u306f\u3001\u80ba\u304c\u6700\u3082\u591a\u304f\u3001\u6b21\u3044\u3067\u8133\u3001\u9aa8\u3001\u809d\u81d3\u306e\u9806\u3067\u8ee2\u79fb\u304c\u591a\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u9069\u5207\u306a\u5c40\u6240\u6cbb\u7642\u304c\u3055\u308c\u3066\u3044\u308c\u3070\u3001\u9818\u57df\u30ea\u30f3\u30d1\u7bc0\u306e\u518d\u767a\u306f\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n

      Q:\u00a0\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306b\u3064\u3044\u3066\u3044\u308d\u3044\u308d\u6559\u3048\u3066\u304f\u3060\u3055\u3044\uff08\u96d1\u5b66\u7684\u306a\u77e5\u8b58\u3067\u69cb\u3044\u307e\u305b\u3093\uff09<\/strong><\/span><\/h4>\n

      \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09\u3068\u306f\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u304a\u3088\u3073\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u3082\u3001\u30d2\u30c8\u4e0a\u76ae\u6210\u9577\u56e0\u5b50\u53d7\u5bb9\u4f53\uff08HER\uff09\u306e\u904e\u5270\u767a\u73fe\u3084\u5897\u5e45\u3082\u8a8d\u3081\u3089\u308c\u306a\u3044\u4e73\u304c\u3093\u3067\u3001\u4e73\u304c\u3093\u306e\u7d0415\uff05\u3092\u5360\u3081\u307e\u3059\u3002TNBC\u306f\u3001\u75be\u60a3\u7d4c\u904e\u306e\u65e9\u671f\u306b\u8ee2\u79fb\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u4e88\u5f8c\u306e\u60aa\u3044\u5185\u81d3\u3084\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u8ee2\u79fb\u304c\u767a\u751f\u3057\u3084\u3059\u3044\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002BRCA\u907a\u4f1d\u5b50\u306e\u75c5\u7684\u5909\u7570\u306fTNBC\u60a3\u8005\u306e\u7d0420\uff05\u306b\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002TNBC\u306f\u3001\u30a2\u30b8\u30a2\u4eba\u3084\u975e\u30d2\u30b9\u30d1\u30cb\u30c3\u30af\u7cfb\u306e\u767d\u4eba\u5973\u6027\u3088\u308a\u3082\u3001\u9ed2\u4eba\u3084\u30d2\u30b9\u30d1\u30cb\u30c3\u30af\u7cfb\u306e\u5973\u6027\u306b\u591a\u304f\u767a\u75c7\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n

      \u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u3092\u7528\u3044\u3066\u3001\u816b\u760d\u306b\u7279\u7570\u7684\u306a4\u3064\u306eTNBC\u30b5\u30d6\u30bf\u30a4\u30d7\u304c\u540c\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u30012\u3064\u306e\u57fa\u5e95\u69d8\u30b5\u30d6\u30bf\u30a4\u30d7\uff08BL1\u3001BL2\uff09\u3001\u816b\u760d\u6d78\u6f64\u30ea\u30f3\u30d1\u7403\u3068\u816b\u760d\u95a2\u9023\u9593\u8449\u7cfb\u7d30\u80de\u3092\u7279\u5fb4\u3068\u3059\u308b\u30b5\u30d6\u30bf\u30a4\u30d7\uff08M\uff09\u3001\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08LAR\uff09\u3092\u4ecb\u3057\u3066\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u30eb\u30df\u30ca\u30eb\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3059\u3002\u4e2d\u3067\u3082BL1-TNBC\u304c\u6700\u3082\u591a\u304f\u3001TNBC\u60a3\u8005\u306e\u7d0435\uff05\u3092\u5360\u3081\u307e\u3059\u3002\u3053\u308c\u3089\u306eTNBC\u30b5\u30d6\u30bf\u30a4\u30d7\u306f\u3001\u8a3a\u65ad\u6642\u306e\u5e74\u9f62\u3001\u60aa\u6027\u5ea6\u3001\u5c40\u6240\u304a\u3088\u3073\u9060\u9694\u306e\u75c5\u52e2\u9032\u884c\u3001\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u6240\u898b\u306e\u9055\u3044\u306b\u52a0\u3048\u3066\u3001\u5229\u7528\u53ef\u80fd\u306a\u6cbb\u7642\u6cd5\u3078\u306e\u53cd\u5fdc\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001BL1\u30b5\u30d6\u30bf\u30a4\u30d7\u306e\u60a3\u8005\u3055\u3093\u306f\u3001BL2\u30b5\u30d6\u30bf\u30a4\u30d7\u3084LAR\u30b5\u30d6\u30bf\u30a4\u30d7\u306e\u60a3\u8005\u3055\u3093\u3068\u6bd4\u8f03\u3057\u3066\u3001\u540c\u69d8\u306e\u30cd\u30aa\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u5316\u5b66\u7642\u6cd5\u306b\u3088\u308b\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\u7387\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002LAR-TNBC\u30b5\u30d6\u30bf\u30a4\u30d7\u306f\u30014\u3064\u306e\u30b5\u30d6\u30bf\u30a4\u30d7\u306e\u4e2d\u3067\u6700\u3082\u5c11\u306a\u3044\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3059\u304c\u3001\u8a3a\u65ad\u6642\u306b\u9589\u7d4c\u5f8c\u3067\u3042\u3063\u305f\u5973\u6027TNBC\u60a3\u8005\u306b\u6700\u3082\u591a\u304f\u898b\u3089\u308c\u307e\u3059\u3002<\/strong><\/span><\/p>\n

      Atezolizumab\u3068nab-\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u306e\u4f75\u7528\u7642\u6cd5\u306f\u3001\u816b\u760d\u304cPD-L1\u3092\u767a\u73fe\u3057\u3066\u3044\u308b\u5207\u9664\u4e0d\u80fd\u306a\u5c40\u6240\u9032\u884c\u6027\u307e\u305f\u306f\u8ee2\u79fb\u6027TNBC\u60a3\u8005\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30b5\u30b7\u30c4\u30ba\u30de\u30d6\u30fb\u30b4\u30d3\u30c6\u30ab\u30f3\u306f\u3001\u8ee2\u79fb\u6027\u75be\u60a3\u306b\u5bfe\u3057\u30662\u7a2e\u985e\u4ee5\u4e0a\u306e\u524d\u6cbb\u7642\u3092\u53d7\u3051\u305f\u3053\u3068\u306e\u3042\u308b\u60a3\u8005\u306e\u8ee2\u79fb\u6027TNBC\u306e\u6cbb\u7642\u306b\u9069\u5fdc\u3055\u308c\u307e\u3059\u3002BRCA\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6709\u3059\u308b\u8ee2\u79fb\u6027TNBC\u60a3\u8005\u306f\u3001\u30c9\u30bb\u30bf\u30ad\u30bb\u30eb\u3088\u308a\u3082\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u3092\u7528\u3044\u305f\u6cbb\u7642\u306b\u53cd\u5fdc\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002PARP\u963b\u5bb3\u5264\u306f\u3001BRCA\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6709\u3059\u308b\u9032\u884c\u6027TNBC\u60a3\u8005\u306b\u304a\u3044\u3066\u660e\u78ba\u306a\u52b9\u679c\u3092\u793a\u3057\u307e\u3059\u3002<\/strong><\/span><\/p>\n

      \u65e9\u671f\u3067\u5207\u9664\u53ef\u80fd\u306aTNBC\u3084\u5316\u5b66\u7642\u6cd5\u306b\u611f\u53d7\u6027\u306e\u9ad8\u3044\u4ed6\u306e\u4e73\u764c\u306e\u60a3\u8005\u306b\u306f\u3001\u30cd\u30aa\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u671b\u307e\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8853\u524d\u5316\u5b66\u7642\u6cd5\u306b\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u65e9\u671fTNBC\u60a3\u8005\u306e\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u306b\u304a\u3051\u308bTNBC\u3078\u306e\u767d\u91d1\u88fd\u5264\uff08\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u304a\u3088\u3073\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\uff09\u306e\u4f7f\u7528\u306b\u95a2\u3059\u308b\u30c7\u30fc\u30bf\u306f\u4e0d\u8db3\u3057\u3066\u304a\u308a\u3001\u3057\u305f\u304c\u3063\u3066\u3001\u3053\u306e\u8a2d\u5b9a\u3067\u306f\u767d\u91d1\u88fd\u5264\u3092\u63a8\u5968\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u767d\u91d1\u88fd\u5264\u306f\u3001\u751f\u6b96\u7d30\u80de\u7cfbBRCA 1\/2\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6709\u3059\u308b\u518d\u767a\u307e\u305f\u306f\u30b9\u30c6\u30fc\u30b8IV\u306eTNBC\u60a3\u8005\u306e\u6cbb\u7642\u306b\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u518d\u767a\u306e\u30d5\u30a1\u30fc\u30b9\u30c8\u30e9\u30a4\u30f3\u6cbb\u7642\u3067\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u3068\u5316\u5b66\u7642\u6cd5\u3092\u4f75\u7528\u3059\u308b\u3068\u3001\u9ad8\u3044\u594f\u52b9\u7387\u304c\u5f97\u3089\u308c\u307e\u3059\u3002<\/strong><\/span><\/p>\n

      \"\"

      The Okura Tokyo<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

      \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\uff08TNBC\uff09\u7279\u5fb4\u306b\u3064\u3044\u3066\u6559\u3048\u3066\u304f\u3060\u3055\u3044 1. \u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u6b20\u5982 TNBC\u306f\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08ER\uff09\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53\uff08PR\uff09\u3001\u304a\u3088\u3073HER2\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u3044\u305a\u308c\u3082\u767a\u73fe\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u300c\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3084HER2\u306b\u5bfe\u3059\u308b\u6a19\u7684\u7642\u6cd5\u304c\u52b9\u679c\u3092\u793a\u3055\u305a\u3001\u4ed6\u306e\u4e73\u764c\u30bf\u30a4\u30d7\u3068\u306f\u7570\u306a\u308b\u6cbb\u7642\u304c\u5fc5\u8981\u3067\u3059\u3002 2. \u9032\u884c\u306e\u901f\u3055 TNBC\u306f\u4e00\u822c\u7684\u306b\u5897\u6b96\u304c\u65e9\u304f\u3001\u8a3a\u65ad\u6642\u306b\u306f\u9032\u884c\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u4ed6\u306e\u4e73\u764c\u306b\u6bd4\u3079\u3066\u60aa\u6027\u5ea6\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u65e9\u671f\u306b\u8ee2\u79fb\u3059\u308b\u30ea\u30b9\u30af\u304c\u3042\u308a\u3001\u518d\u767a\u7387\u3082\u6bd4\u8f03\u7684\u9ad8\u3044\u3067\u3059\u3002 3. \u4e88\u5f8c\u306e\u53b3\u3057\u3055 TNBC\u306f\u518d\u767a\u7387\u304c\u9ad8\u304f\u3001\u7279\u306b\u6cbb\u7642\u5f8c5\u5e74\u4ee5\u5185\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u4e73\u764c\u3088\u308a\u9ad8\u3044\u3067\u3059\u3002\u305f\u3060\u3057\u3001\u5316\u5b66\u7642\u6cd5\u306b\u306f\u6bd4\u8f03\u7684\u611f\u53d7\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u65e9\u671f\u767a\u898b\u3068\u9069\u5207\u306a\u6cbb\u7642\u306b\u3088\u308a\u4e88\u5f8c\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 4. \u82e5\u5e74\u5973\u6027\u306b\u591a\u3044 TNBC\u306f\u4ed6\u306e\u4e73\u764c\u306b\u6bd4\u3079\u3066\u3001\u82e5\u5e74\u5973\u6027\uff0840\u6b73\u4ee5\u4e0b\uff09\u306b\u767a\u75c7\u3057\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u30a2\u30d5\u30ea\u30ab\u7cfb\u3084\u30d2\u30b9\u30d1\u30cb\u30c3\u30af\u7cfb\u306e\u5973\u6027\u306b\u591a\u304f\u898b\u3089\u308c\u307e\u3059\u3002 5. 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