{"id":600,"date":"2024-10-30T00:25:39","date_gmt":"2024-10-29T15:25:39","guid":{"rendered":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/?p=600"},"modified":"2024-10-30T00:25:39","modified_gmt":"2024-10-29T15:25:39","slug":"her2%e9%99%bd%e6%80%a7%e3%82%bf%e3%82%a4%e3%83%97%e3%81%ae%e9%9d%9e%e6%b5%b8%e6%bd%a4%e3%81%8c%e3%82%93%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/approach\/her2%e9%99%bd%e6%80%a7%e3%82%bf%e3%82%a4%e3%83%97%e3%81%ae%e9%9d%9e%e6%b5%b8%e6%bd%a4%e3%81%8c%e3%82%93%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"HER2\u967d\u6027\u30bf\u30a4\u30d7\u306e\u975e\u6d78\u6f64\u304c\u3093\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066"},"content":{"rendered":"
\n
\n
\n
\n

HER2\u967d\u6027\u30bf\u30a4\u30d7\u306e\u975e\u6d78\u6f64\u304c\u3093\uff08DCIS: Ductal Carcinoma in Situ\uff09\u306b\u95a2\u3059\u308b\u8a3a\u65ad\u3068\u6cbb\u7642\u306b\u3064\u3044\u3066\u4ee5\u4e0b\u306b\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n

1. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u3068\u306f<\/h3>\n

HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u3068\u306f\u3001\u4e73\u7ba1\u306e\u5185\u5074\u3067\u304c\u3093\u7d30\u80de\u304c\u5897\u6b96\u3057\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u4e73\u7ba1\u306e\u5916\u306b\u6d78\u6f64\u3057\u3066\u3044\u306a\u3044\u72b6\u614b\u306e\u4e73\u304c\u3093\u3067\u3059\u3002HER2\uff08Human Epidermal growth factor Receptor 2\uff09\u306f\u7d30\u80de\u8868\u9762\u306b\u3042\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4e00\u7a2e\u3067\u3001\u3053\u306e\u53d7\u5bb9\u4f53\u304c\u904e\u5270\u306b\u767a\u73fe\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u304c\u4fc3\u9032\u3055\u308c\u307e\u3059\u3002HER2\u304c\u967d\u6027\u306e\u4e73\u304c\u3093\u306f\u3001\u4e00\u822c\u7684\u306b\u5897\u6b96\u304c\u65e9\u304f\u3001\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u65e9\u671f\u306e\u975e\u6d78\u6f64\u304c\u3093\u3067\u3042\u308c\u3070\u6cbb\u7642\u306b\u3088\u308a\u4e88\u5f8c\u304c\u826f\u597d\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n

2. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u8a3a\u65ad<\/h3>\n

HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306f\u4e3b\u306b\u753b\u50cf\u691c\u67fb\u3084\u75c5\u7406\u8a3a\u65ad\u306b\u3088\u308a\u7279\u5b9a\u3055\u308c\u307e\u3059\u3002<\/p>\n

2.1. \u753b\u50cf\u691c\u67fb<\/h4>\n
    \n
  • \u30de\u30f3\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc<\/strong>\uff1a\u4e73\u817a\u306e\u72b6\u614b\u3092\u8abf\u3079\u308b\u57fa\u672c\u7684\u306a\u691c\u67fb\u3067\u3001\u7279\u306b\u77f3\u7070\u5316\u3092\u4f34\u3046\u4e73\u7ba1\u5185\u306e\u7570\u5e38\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u975e\u6d78\u6f64\u304c\u3093\u306f\u5c0f\u3055\u306a\u77f3\u7070\u5316\u3068\u3057\u3066\u73fe\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u65e9\u671f\u767a\u898b\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/li>\n
  • \u8d85\u97f3\u6ce2\u691c\u67fb\uff08\u30a8\u30b3\u30fc\uff09<\/strong>\uff1a\u4e73\u817a\u306e\u539a\u307f\u3084\u816b\u7624\u306e\u6709\u7121\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u307e\u3059\u3002\u30de\u30f3\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u8a3a\u65ad\u306e\u7cbe\u5ea6\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002<\/li>\n
  • MRI\u691c\u67fb<\/strong>\uff1a\u3088\u308a\u8a73\u7d30\u306a\u4e73\u817a\u306e\u753b\u50cf\u3092\u5f97\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u7279\u306b\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u3084\u975e\u5178\u578b\u7684\u306a\u75c7\u4f8b\u3067\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n

    2.2. \u751f\u691c\u3068\u75c5\u7406\u8a3a\u65ad<\/h4>\n

    \u7591\u308f\u3057\u3044\u75c5\u5909\u304c\u767a\u898b\u3055\u308c\u305f\u5834\u5408\u3001\u7d44\u7e54\u751f\u691c\u304c\u884c\u308f\u308c\u3001\u75c5\u7406\u8a3a\u65ad\u304c\u78ba\u5b9a\u3057\u307e\u3059\u3002HER2\u967d\u6027\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u65b9\u6cd5\u3067HER2\u767a\u73fe\u306e\u8a55\u4fa1\u304c\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n

      \n
    • \u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\uff08IHC\uff09<\/strong>\uff1aHER2\u30bf\u30f3\u30d1\u30af\u306e\u767a\u73fe\u30ec\u30d9\u30eb\u3092\u8a55\u4fa1\u3059\u308b\u65b9\u6cd5\u3067\u3001\u30b9\u30b3\u30a2\u304c3+\u3067\u3042\u308c\u3070HER2\u967d\u6027\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3059\u3002\u30b9\u30b3\u30a2\u304c2+\u306e\u5834\u5408\u306f\u3001\u8ffd\u52a0\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n
    • FISH\uff08\u86cd\u5149in situ\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\uff09\u6cd5<\/strong>\uff1aIHC\u30b9\u30b3\u30a2\u304c2+\u3067\u3042\u3063\u305f\u5834\u5408\u306b\u3001HER2\u907a\u4f1d\u5b50\u306e\u5897\u5e45\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306e\u691c\u67fb\u3067\u3001\u3053\u308c\u306b\u3088\u308aHER2\u306e\u967d\u6027\u3092\u78ba\u5b9a\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n

      2.3. \u305d\u306e\u4ed6\u306e\u8a3a\u65ad\u691c\u67fb<\/h4>\n
        \n
      • \u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u691c\u67fb<\/strong>\uff1aHER2\u967d\u6027\u3067\u3042\u3063\u3066\u3082\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u306eDCIS\u306f\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3082\u8003\u616e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n

        3. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u6cbb\u7642<\/h3>\n

        HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u6cbb\u7642\u306f\u3001\u4e3b\u306b\u5916\u79d1\u7684\u624b\u8853\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u3001\u305d\u3057\u3066\u4e00\u90e8\u306e\u75c7\u4f8b\u3067\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u304c\u8003\u616e\u3055\u308c\u307e\u3059\u3002<\/p>\n

        3.1. \u5916\u79d1\u7684\u624b\u8853<\/h4>\n
          \n
        • \u4e73\u623f\u6e29\u5b58\u624b\u8853<\/strong>\uff1a\u4e73\u623f\u5168\u4f53\u306e\u6458\u51fa\u3092\u907f\u3051\u3001\u816b\u760d\u90e8\u5206\u306e\u307f\u3092\u5207\u9664\u3059\u308b\u624b\u8853\u3067\u3059\u3002HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u3067\u3082\u3001\u5468\u56f2\u306e\u6b63\u5e38\u7d44\u7e54\u3068\u3068\u3082\u306b\u816b\u760d\u3092\u5b8c\u5168\u306b\u6458\u51fa\u3059\u308b\u3053\u3068\u3067\u6cbb\u7652\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/li>\n
        • \u4e73\u623f\u5168\u6458\u624b\u8853<\/strong>\uff1a\u5e83\u7bc4\u56f2\u306bDCIS\u304c\u5e83\u304c\u3063\u3066\u3044\u308b\u5834\u5408\u3084\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u5224\u65ad\u3055\u308c\u308b\u5834\u5408\u3001\u4e73\u623f\u5168\u6458\u304c\u9078\u629e\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u4e73\u623f\u5168\u6458\u8853\u5f8c\u306e\u518d\u767a\u30ea\u30b9\u30af\u306f\u975e\u5e38\u306b\u4f4e\u304f\u306a\u308a\u307e\u3059\u304c\u3001\u60a3\u8005\u306e\u751f\u6d3b\u306e\u8cea\u3082\u8003\u616e\u3057\u3066\u9078\u629e\u3055\u308c\u308b\u3079\u304d\u3067\u3059\u3002<\/li>\n<\/ul>\n

          3.2. \u653e\u5c04\u7dda\u6cbb\u7642<\/h4>\n

          \u4e73\u623f\u6e29\u5b58\u624b\u8853\u5f8c\u306b\u306f\u901a\u5e38\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u3088\u308a\u6b8b\u5b58\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u304c\u3093\u7d30\u80de\u3092\u7834\u58ca\u3057\u3001\u518d\u767a\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3055\u305b\u307e\u3059\u3002DCIS\u3067\u306f\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u6709\u7121\u306b\u3088\u3063\u3066\u518d\u767a\u7387\u304c\u5927\u304d\u304f\u5909\u308f\u308b\u305f\u3081\u3001\u6a19\u6e96\u6cbb\u7642\u306e\u4e00\u90e8\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

          3.3. \u5206\u5b50\u6a19\u7684\u6cbb\u7642\uff08\u6297HER2\u7642\u6cd5\uff09<\/h4>\n

          \u975e\u6d78\u6f64\u304c\u3093\u306b\u304a\u3051\u308b\u6297HER2\u7642\u6cd5\u306e\u6709\u52b9\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u73fe\u5728\u3082\u7814\u7a76\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u6cbb\u7642\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002\u6297HER2\u7642\u6cd5\u306b\u306f\u3001\u4e3b\u306b\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6\u3084\u30da\u30eb\u30c4\u30ba\u30de\u30d6\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u304c\u3001\u975e\u6d78\u6f64\u304c\u3093\u306e\u5834\u5408\u3001\u5fc5\u305a\u3057\u3082\u6a19\u6e96\u6cbb\u7642\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

            \n
          • \u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6<\/strong>\uff1aHER2\u967d\u6027\u4e73\u304c\u3093\u306e\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u308b\u6297\u4f53\u85ac\u3067\u3001HER2\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3066\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u6d78\u6f64\u304c\u3093\u3067\u306f\u6709\u52b9\u6027\u304c\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001DCIS\u3067\u306f\u9069\u5fdc\u5916\u3067\u3042\u308a\u3001\u81e8\u5e8a\u8a66\u9a13\u306a\u3069\u3067\u306e\u4f7f\u7528\u304c\u4e3b\u3067\u3059\u3002<\/li>\n
          • \u81e8\u5e8a\u8a66\u9a13\u306e\u73fe\u72b6<\/strong>\uff1a\u73fe\u5728\u3001HER2\u967d\u6027\u306e\u975e\u6d78\u6f64\u304c\u3093\u306b\u5bfe\u3059\u308b\u6297HER2\u7642\u6cd5\u306e\u6709\u52b9\u6027\u3084\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u304c\u9032\u3093\u3067\u304a\u308a\u3001\u4eca\u5f8c\u306e\u7d50\u679c\u6b21\u7b2c\u3067\u306f\u6a19\u6e96\u6cbb\u7642\u306b\u7d44\u307f\u8fbc\u307e\u308c\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n

            3.4. \u30db\u30eb\u30e2\u30f3\u7642\u6cd5<\/h4>\n

            HER2\u967d\u6027\u3067\u3042\u3063\u3066\u3082\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u3082\u967d\u6027\u306e\u5834\u5408\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3084\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\u3068\u3044\u3063\u305f\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u304c\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u8003\u616e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u9589\u7d4c\u5f8c\u306e\u5973\u6027\u306b\u5bfe\u3057\u3066\u306f\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u518d\u767a\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

            4. \u518d\u767a\u4e88\u9632\u3068\u7d4c\u904e\u89b3\u5bdf<\/h3>\n

            HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u6cbb\u7642\u5f8c\u306f\u3001\u518d\u767a\u30ea\u30b9\u30af\u304c\u6bd4\u8f03\u7684\u9ad8\u3044\u305f\u3081\u3001\u7d4c\u904e\u89b3\u5bdf\u304c\u91cd\u8981\u3067\u3059\u3002\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u65b9\u6cd5\u3067\u518d\u767a\u30ea\u30b9\u30af\u306e\u8efd\u6e1b\u3084\u65e9\u671f\u767a\u898b\u306b\u52aa\u3081\u307e\u3059\u3002<\/p>\n

            4.1. \u5b9a\u671f\u7684\u306a\u753b\u50cf\u691c\u67fb<\/h4>\n

            \u6cbb\u7642\u5f8c\u306e\u518d\u767a\u3084\u65b0\u305f\u306a\u75c5\u5909\u306e\u767a\u751f\u3092\u65e9\u671f\u306b\u767a\u898b\u3059\u308b\u305f\u3081\u306b\u3001\u5b9a\u671f\u7684\u306a\u30de\u30f3\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u3084\u8d85\u97f3\u6ce2\u691c\u67fb\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u4e73\u623f\u518d\u5efa\u8853\u3092\u53d7\u3051\u305f\u5834\u5408\u3067\u3082\u5b9a\u671f\u7684\u306a\u691c\u67fb\u306f\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

            4.2. \u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584<\/h4>\n

            \u518d\u767a\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u305f\u3081\u306b\u3001\u98df\u751f\u6d3b\u3084\u904b\u52d5\u7fd2\u6163\u3092\u898b\u76f4\u3059\u3053\u3068\u304c\u6709\u52b9\u3067\u3059\u3002\u7279\u306b\u80a5\u6e80\u3084\u98f2\u9152\u3001\u55ab\u7159\u306f\u4e73\u304c\u3093\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n

            4.3. \u30b5\u30dd\u30fc\u30c8\u4f53\u5236\u306e\u6d3b\u7528<\/h4>\n

            \u5fc3\u7406\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u3084\u533b\u7642\u30c1\u30fc\u30e0\u3068\u306e\u9023\u643a\u3082\u518d\u767a\u4e88\u9632\u306b\u306f\u91cd\u8981\u3067\u3059\u3002\u6cbb\u7642\u5f8c\u306e\u4e0d\u5b89\u3084\u751f\u6d3b\u306e\u8cea\u306b\u95a2\u3059\u308b\u554f\u984c\u3092\u89e3\u6c7a\u3059\u308b\u305f\u3081\u3001\u533b\u7642\u30b9\u30bf\u30c3\u30d5\u3084\u30ab\u30a6\u30f3\u30bb\u30e9\u30fc\u3001\u30b5\u30dd\u30fc\u30c8\u30b0\u30eb\u30fc\u30d7\u306e\u652f\u63f4\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n

            5. \u307e\u3068\u3081<\/h3>\n

            HER2\u967d\u6027\u306e\u975e\u6d78\u6f64\u304c\u3093\u306f\u3001\u4e73\u304c\u3093\u306e\u4e2d\u3067\u3082\u6bd4\u8f03\u7684\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30bf\u30a4\u30d7\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u65e9\u671f\u767a\u898b\u3068\u9069\u5207\u306a\u6cbb\u7642\u306b\u3088\u308a\u826f\u597d\u306a\u4e88\u5f8c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u8a3a\u65ad\u306b\u306f\u753b\u50cf\u691c\u67fb\u3084\u75c5\u7406\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u6cbb\u7642\u306b\u306f\u5916\u79d1\u7684\u624b\u8853\u3084\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u6297HER2\u7642\u6cd5\u3084\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u306f\u3001\u75c7\u4f8b\u306b\u3088\u3063\u3066\u8003\u616e\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u306b\u3088\u308a\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u304c\u5c0e\u5165\u3055\u308c\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u6cbb\u7642\u5f8c\u306e\u7d4c\u904e\u89b3\u5bdf\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u306b\u3088\u308a\u3001\u518d\u767a\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

            \n
            \n
            <\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

            HER2\u967d\u6027\u30bf\u30a4\u30d7\u306e\u975e\u6d78\u6f64\u304c\u3093\uff08DCIS: Ductal Carcinoma in Situ\uff09\u306b\u95a2\u3059\u308b\u8a3a\u65ad\u3068\u6cbb\u7642\u306b\u3064\u3044\u3066\u4ee5\u4e0b\u306b\u307e\u3068\u3081\u307e\u3059\u3002 1. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u3068\u306f HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u3068\u306f\u3001\u4e73\u7ba1\u306e\u5185\u5074\u3067\u304c\u3093\u7d30\u80de\u304c\u5897\u6b96\u3057\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u4e73\u7ba1\u306e\u5916\u306b\u6d78\u6f64\u3057\u3066\u3044\u306a\u3044\u72b6\u614b\u306e\u4e73\u304c\u3093\u3067\u3059\u3002HER2\uff08Human Epidermal growth factor Receptor 2\uff09\u306f\u7d30\u80de\u8868\u9762\u306b\u3042\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4e00\u7a2e\u3067\u3001\u3053\u306e\u53d7\u5bb9\u4f53\u304c\u904e\u5270\u306b\u767a\u73fe\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u304c\u4fc3\u9032\u3055\u308c\u307e\u3059\u3002HER2\u304c\u967d\u6027\u306e\u4e73\u304c\u3093\u306f\u3001\u4e00\u822c\u7684\u306b\u5897\u6b96\u304c\u65e9\u304f\u3001\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u65e9\u671f\u306e\u975e\u6d78\u6f64\u304c\u3093\u3067\u3042\u308c\u3070\u6cbb\u7642\u306b\u3088\u308a\u4e88\u5f8c\u304c\u826f\u597d\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002 2. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u8a3a\u65ad HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306f\u4e3b\u306b\u753b\u50cf\u691c\u67fb\u3084\u75c5\u7406\u8a3a\u65ad\u306b\u3088\u308a\u7279\u5b9a\u3055\u308c\u307e\u3059\u3002 2.1. \u753b\u50cf\u691c\u67fb \u30de\u30f3\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\uff1a\u4e73\u817a\u306e\u72b6\u614b\u3092\u8abf\u3079\u308b\u57fa\u672c\u7684\u306a\u691c\u67fb\u3067\u3001\u7279\u306b\u77f3\u7070\u5316\u3092\u4f34\u3046\u4e73\u7ba1\u5185\u306e\u7570\u5e38\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u975e\u6d78\u6f64\u304c\u3093\u306f\u5c0f\u3055\u306a\u77f3\u7070\u5316\u3068\u3057\u3066\u73fe\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u65e9\u671f\u767a\u898b\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002 \u8d85\u97f3\u6ce2\u691c\u67fb\uff08\u30a8\u30b3\u30fc\uff09\uff1a\u4e73\u817a\u306e\u539a\u307f\u3084\u816b\u7624\u306e\u6709\u7121\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u307e\u3059\u3002\u30de\u30f3\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u8a3a\u65ad\u306e\u7cbe\u5ea6\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002 MRI\u691c\u67fb\uff1a\u3088\u308a\u8a73\u7d30\u306a\u4e73\u817a\u306e\u753b\u50cf\u3092\u5f97\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u7279\u306b\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u3084\u975e\u5178\u578b\u7684\u306a\u75c7\u4f8b\u3067\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002 2.2. \u751f\u691c\u3068\u75c5\u7406\u8a3a\u65ad \u7591\u308f\u3057\u3044\u75c5\u5909\u304c\u767a\u898b\u3055\u308c\u305f\u5834\u5408\u3001\u7d44\u7e54\u751f\u691c\u304c\u884c\u308f\u308c\u3001\u75c5\u7406\u8a3a\u65ad\u304c\u78ba\u5b9a\u3057\u307e\u3059\u3002HER2\u967d\u6027\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u65b9\u6cd5\u3067HER2\u767a\u73fe\u306e\u8a55\u4fa1\u304c\u884c\u308f\u308c\u307e\u3059\u3002 \u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\uff08IHC\uff09\uff1aHER2\u30bf\u30f3\u30d1\u30af\u306e\u767a\u73fe\u30ec\u30d9\u30eb\u3092\u8a55\u4fa1\u3059\u308b\u65b9\u6cd5\u3067\u3001\u30b9\u30b3\u30a2\u304c3+\u3067\u3042\u308c\u3070HER2\u967d\u6027\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3059\u3002\u30b9\u30b3\u30a2\u304c2+\u306e\u5834\u5408\u306f\u3001\u8ffd\u52a0\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002 FISH\uff08\u86cd\u5149in situ\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\uff09\u6cd5\uff1aIHC\u30b9\u30b3\u30a2\u304c2+\u3067\u3042\u3063\u305f\u5834\u5408\u306b\u3001HER2\u907a\u4f1d\u5b50\u306e\u5897\u5e45\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306e\u691c\u67fb\u3067\u3001\u3053\u308c\u306b\u3088\u308aHER2\u306e\u967d\u6027\u3092\u78ba\u5b9a\u3057\u307e\u3059\u3002 2.3. \u305d\u306e\u4ed6\u306e\u8a3a\u65ad\u691c\u67fb \u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u691c\u67fb\uff1aHER2\u967d\u6027\u3067\u3042\u3063\u3066\u3082\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u306eDCIS\u306f\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3082\u8003\u616e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 3. HER2\u967d\u6027\u975e\u6d78\u6f64\u304c\u3093\u306e\u6cbb\u7642 HER2\u30fb\u30fb\u30fb<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[32,28,13,2],"tags":[],"class_list":["post-600","post","type-post","status-publish","format-standard","hentry","category-32","category-her2","category-13","category-approach"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/600"}],"collection":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/comments?post=600"}],"version-history":[{"count":1,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/600\/revisions"}],"predecessor-version":[{"id":601,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/600\/revisions\/601"}],"wp:attachment":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/media?parent=600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/categories?post=600"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/tags?post=600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}