{"id":647,"date":"2025-09-07T22:53:34","date_gmt":"2025-09-07T13:53:34","guid":{"rendered":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/?p=647"},"modified":"2025-12-08T00:47:08","modified_gmt":"2025-12-07T15:47:08","slug":"tnbc%e3%81%ae%e7%89%b9%e6%ae%8a%e5%9e%8b%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/%e3%83%88%e3%83%aa%e3%83%97%e3%83%ab%e3%83%8d%e3%82%ac%e3%83%86%e3%82%a3%e3%83%96%e4%b9%b3%e3%81%8c%e3%82%93\/tnbc%e3%81%ae%e7%89%b9%e6%ae%8a%e5%9e%8b%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u30bf\u30a4\u30d7\u306e\u65e9\u671f\u4e73\u764c\u306e\u7279\u6b8a\u578b\u306e\u89e3\u8aac\u3001\u307e\u305f\u305d\u306e\u85ac\u7269\u7642\u6cd5\u306e\u5185\u5bb9\u306b\u3064\u3044\u3066"},"content":{"rendered":"
\n

\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\uff08Triple Negative Breast Cancer: TNBC<\/b>\uff09\u30bf\u30a4\u30d7\u306e\u4e73\u764c\u306f\u3001\u4e73\u764c\u5168\u4f53\u306e\u7d0415\u301c20%\u3092\u5360\u3081\u308b\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3059\u3002\u3053\u306e\u30bf\u30a4\u30d7\u306f\u3001\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\uff08\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53 ER<\/b>\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53 PgR<\/b>\uff09\u304a\u3088\u3073\u30d2\u30c8\u4e0a\u76ae\u5897\u6b96\u56e0\u5b50\u53d7\u5bb9\u4f532\u578b\uff08HER2<\/b>\uff09\u304c\u3059\u3079\u3066\u9670\u6027\u3067\u3042\u308b\u3068\u3044\u3046\u7279\u5fb4\u3092\u6301\u3061\u3001\u5185\u5206\u6ccc\u7642\u6cd5\u3084\u6297HER2\u7642\u6cd5\u304c\u52b9\u304b\u305a\u3001\u4e3b\u306b\u5316\u5b66\u7642\u6cd5<\/b>\u304c\u6cbb\u7642\u306e\u4e3b\u8ef8\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n

TNBC\u306e\u591a\u304f\u306f\u3001\u7279\u6b8a\u306a\u7d44\u7e54\u50cf\u3092\u6301\u305f\u306a\u3044\u6d78\u6f64\u6027\u4e73\u7ba1\u764c\u306e\u975e\u7279\u6b8a\u578b\uff08IDC-NST\uff09\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u304c\u3001\u4e00\u90e8\u306b\u306f\u4e88\u5f8c\u3084\u6cbb\u7642\u53cd\u5fdc\u6027\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u7279\u6b8a\u578b<\/b>\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7279\u6b8a\u578b\u3092\u6b63\u78ba\u306b\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3001\u60a3\u8005\u3055\u3093\u306b\u3068\u3063\u3066\u9069\u5207\u306a\u6cbb\u7642\u6226\u7565\uff08\u7279\u306b\u5316\u5b66\u7642\u6cd5\u306e\u5f37\u5ea6\uff09\u3092\u9078\u629e\u3059\u308b\u305f\u3081\u306b\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002<\/p>\n

\u672c\u7a3f\u3067\u306f\u3001\u65e9\u671f\u4e73\u764c\u306b\u304a\u3051\u308bTNBC\u306e\u7279\u6b8a\u578b\u306b\u7126\u70b9\u3092\u5f53\u3066\u3001\u305d\u306e\u75c5\u7406\u5b66\u7684\u7279\u5fb4\u3068\u3001\u5404\u7279\u6b8a\u578b\u304a\u3088\u3073\u6a19\u6e96TNBC\u306b\u5bfe\u3059\u308b\u85ac\u7269\u7642\u6cd5\u306e\u6700\u65b0\u306e\u5185\u5bb9\u306b\u3064\u3044\u3066\u3001\u8a73\u7d30\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n

\n

1. \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\uff08TNBC\uff09\u306e\u6982\u8981<\/h2>\n

TNBC\u306f\u3001\u4ee5\u4e0b\u306e\u751f\u7269\u5b66\u7684\u7279\u5fb4\u3092\u6301\u3061\u307e\u3059\u3002<\/p>\n

    \n
  • \n

    \u9ad8\u60aa\u6027\u5ea6:<\/b> \u7d44\u7e54\u5b66\u7684\u60aa\u6027\u5ea6\uff08HG\uff09\u304c\u9ad8\u304f\u3001\u5897\u6b96\u306e\u6307\u6a19\u3067\u3042\u308bKi67\u304c\u9ad8\u7387\uff0860%\u4ee5\u4e0a\uff09\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044\u3002<\/p>\n<\/li>\n

  • \n

    \u4e88\u5f8c:<\/b> \u6cbb\u7642\u3057\u306a\u3051\u308c\u3070\u4e88\u5f8c\u304c\u60aa\u3044\u304c\u3001\u5316\u5b66\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u65e9\u671f\u306b\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\uff08pCR\uff09\u304c\u5f97\u3089\u308c\u305f\u5834\u5408\u306e\u4e88\u5f8c\u306f\u826f\u597d\u3002<\/p>\n<\/li>\n

  • \n

    \u518d\u767a\u30d1\u30bf\u30fc\u30f3:<\/b> \u8a3a\u65ad\u5f8c5\u5e74\u4ee5\u5185\u306e\u65e9\u671f\u518d\u767a\u304c\u591a\u3044\u3002<\/p>\n<\/li>\n

  • \n

    \u5206\u5b50\u5b66\u7684\u7279\u5fb4:<\/b> \u591a\u304f\u306eTNBC\u306f\u57fa\u5e95\u7d30\u80de\u69d8\uff08Basal-like\uff09\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u3092\u793a\u3057\u3001\u907a\u4f1d\u5b50\u5909\u7570\u4fee\u5fa9\u7d4c\u8def\u306b\u95a2\u308f\u308bBRCA1\/2\u907a\u4f1d\u5b50\u5909\u7570<\/b>\u304c\u9ad8\u3044\u983b\u5ea6\u3067\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

    \n

    2. TNBC\u306e\u7279\u6b8a\u578b\u3068\u305d\u306e\u75c5\u7406\u5b66\u7684\u7279\u5fb4<\/h2>\n

    TNBC\u306b\u5206\u985e\u3055\u308c\u308b\u7279\u6b8a\u578b\u4e73\u764c\u306f\u3001\u5168\u4f53\u306e\u3054\u304f\u4e00\u90e8\u3067\u3059\u304c\u3001\u305d\u306e\u7d44\u7e54\u5b66\u7684\u7279\u5fb4\u304b\u3089\u3001\u901a\u5e38\u306eIDC-NST\u3068\u306f\u7570\u306a\u308b\u751f\u7269\u5b66\u7684\u7279\u6027\u3084\u4e88\u5f8c\u3092\u793a\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

    2-1. \u4e88\u5f8c\u304c\u6bd4\u8f03\u7684\u826f\u597d\u306a\u7279\u6b8a\u578b<\/h3>\n

    \u3053\u308c\u3089\u306e\u7279\u6b8a\u578b\u306fTNBC\u306e\u5b9a\u7fa9\u3092\u6e80\u305f\u3059\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u975e\u7279\u6b8a\u578bTNBC\u306b\u6bd4\u3079\u3066\u4e88\u5f8c\u304c\u6975\u3081\u3066\u826f\u597d<\/b>\u3067\u3042\u308b\u305f\u3081\u3001\u5316\u5b66\u7642\u6cd5\u306e\u9069\u5fdc\u304c\u614e\u91cd\u306b\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002<\/p>\n

    \u2460 \u817a\u69d8\u56a2\u80de\u764c\uff08Adenoid Cystic Carcinoma: AdCC\uff09<\/h4>\n
      \n
    • \n

      \u7279\u5fb4:<\/b> \u975e\u5e38\u306b\u7a00\u306a\u30bf\u30a4\u30d7\u3067\u3001\u4e73\u817a\u5916\u306e\u553e\u6db2\u817a\u3084\u6c17\u7ba1\u652f\u817a\u306b\u3082\u767a\u751f\u3059\u308b\u816b\u760d\u3068\u7d44\u7e54\u50cf\u304c\u985e\u4f3c\u3057\u3066\u3044\u307e\u3059\u3002\u75c5\u7406\u5b66\u7684\u306b\u306f\u3001\u7be9\u72b6\u69cb\u9020\uff08\u3075\u308b\u3044\u306e\u3088\u3046\u306a\u69cb\u9020\uff09\u3084\u7ba1\u72b6\u69cb\u9020\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\u3002<\/p>\n<\/li>\n

    • \n

      TNBC\u3078\u306e\u5206\u985e:<\/b> \u307b\u3068\u3093\u3069\u306eAdCC\u306fER\u30fbPgR\u30fbHER2\u9670\u6027\u3067\u3042\u308a\u3001TNBC\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n

    • \n

      \u4e88\u5f8c:<\/b> \u6975\u3081\u3066\u826f\u597d<\/b>\u3002\u518d\u767a\u306f\u975e\u5e38\u306b\u7a00\u3067\u3001\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3082\u307b\u3068\u3093\u3069\u8d77\u3053\u308a\u307e\u305b\u3093\uff08\u7d041%\uff09\u3002\u9060\u9694\u8ee2\u79fb\u306f\u3055\u3089\u306b\u7a00\u3067\u3059\u3002<\/p>\n<\/li>\n

    • \n

      \u6cbb\u7642\u3078\u306e\u5f71\u97ff:<\/b> \u4e88\u5f8c\u304c\u826f\u3059\u304e\u308b\u305f\u3081\u3001\u8853\u5f8c\u5316\u5b66\u7642\u6cd5\u306e\u6069\u6075\u304c\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u57fa\u672c\u7684\u306b\u5c40\u6240\u7642\u6cd5\uff08\u624b\u8853\u3068\u653e\u5c04\u7dda\u6cbb\u7642\uff09\u304c\u6cbb\u7642\u306e\u4e3b\u4f53<\/b>\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

      \u2461 \u9ac4\u69d8\u764c\uff08Medullary Carcinoma: MC\uff09<\/h4>\n
        \n
      • \n

        \u7279\u5fb4:<\/b> \u816b\u760d\u7d30\u80de\u304c\u7dfb\u5bc6\u306b\u5897\u6b96\u3057\u3001\u30ea\u30f3\u30d1\u7403\u30fb\u5f62\u8cea\u7d30\u80de\u306e\u8457\u3057\u3044\u6d78\u6f64\uff08\u514d\u75ab\u7d30\u80de\u306e\u5f37\u3044\u53cd\u5fdc\uff09\u304c\u898b\u3089\u308c\u307e\u3059\u3002\u816b\u760d\u8fba\u7e01\u304c\u6ed1\u3089\u304b\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n<\/li>\n

      • \n

        TNBC\u3078\u306e\u5206\u985e:<\/b> \u591a\u304f\u306eMC\u306fTNBC\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u304c\u3001\u53b3\u5bc6\u306a\u75c5\u7406\u5b66\u7684\u5b9a\u7fa9\u3092\u6e80\u305f\u3059\u7d14\u7c8b\u306aMC\u306f\u7a00\u3067\u3001\u4e88\u5f8c\u3082\u901a\u5e38\u306eTNBC\u306b\u6bd4\u3079\u3066\u826f\u597d\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n

      • \n

        \u6cbb\u7642\u3078\u306e\u5f71\u97ff:<\/b> \u901a\u5e38\u306eTNBC\u3068\u540c\u69d8\u306b\u5316\u5b66\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u306f\u9ad8\u3044\u3067\u3059\u304c\u3001\u4e88\u5f8c\u304c\u826f\u3044\u305f\u3081\u3001\u5316\u5b66\u7642\u6cd5\u306e\u9069\u5fdc\u304c\u8b70\u8ad6\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

        \u2462 \u5206\u6ccc\u764c\uff08Secretory Carcinoma: SC\uff09<\/h4>\n
          \n
        • \n

          \u7279\u5fb4:<\/b> \u975e\u5e38\u306b\u7a00\u3067\u3001\u7d30\u80de\u5185\u306b\u7a7a\u80de\u3092\u6301\u3061\u3001\u305d\u306e\u4e2d\u306b\u5206\u6ccc\u7269\uff08PAS\u967d\u6027\u7269\u8cea\uff09\u3092\u8caf\u7559\u3057\u3066\u3044\u308b\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002\u82e5\u5e74\u8005\u306b\u591a\u304f\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n

        • \n

          TNBC\u3078\u306e\u5206\u985e:<\/b> \u307b\u3068\u3093\u3069\u304cTNBC\u3067\u3059\u304c\u3001E-Cadherin\u967d\u6027\u306a\u3069\u72ec\u7279\u306a\u514d\u75ab\u67d3\u8272\u30d1\u30bf\u30fc\u30f3\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n<\/li>\n

        • \n

          \u4e88\u5f8c:<\/b> \u6975\u3081\u3066\u826f\u597d<\/b>\u3002\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3082\u5c11\u306a\u304f\u3001\u518d\u767a\u30fb\u8ee2\u79fb\u306e\u30ea\u30b9\u30af\u306f\u975e\u5e38\u306b\u4f4e\u3044\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

          2-2. \u4e88\u5f8c\u304c\u69d8\u3005\u3001\u307e\u305f\u306f\u901a\u5e38\u306eTNBC\u306b\u8fd1\u3044\u7279\u6b8a\u578b<\/h3>\n

          \u2463 \u5316\u751f\u764c\uff08Metaplastic Carcinoma: MpBC\uff09<\/h4>\n
            \n
          • \n

            \u7279\u5fb4:<\/b> TNBC\u306e\u7d045%\u3092\u5360\u3081\u307e\u3059\u3002\u817a\u764c\u6210\u5206\u306b\u52a0\u3048\u3001\u6241\u5e73\u4e0a\u76ae\u764c\u6210\u5206\u3084\u8089\u816b\uff08\u9aa8\u3001\u8edf\u9aa8\u3001\u7dda\u7dad\uff09\u6210\u5206\u306a\u3069\u3001\u975e\u817a\u4e0a\u76ae\u6027\u306e\u6210\u5206\u3092\u542b\u3080\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n<\/li>\n

          • \n

            TNBC\u3078\u306e\u5206\u985e:<\/b> \u307b\u3068\u3093\u3069\u304cTNBC\u3067\u3059\u3002<\/p>\n<\/li>\n

          • \n

            \u4e88\u5f8c:<\/b> \u901a\u5e38\u306eTNBC\u3088\u308a\u4e88\u5f8c\u4e0d\u826f<\/b>\u3068\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n<\/li>\n

          • \n

            \u6cbb\u7642\u3078\u306e\u5f71\u97ff:<\/b> \u901a\u5e38\u306eTNBC\u306e\u5316\u5b66\u7642\u6cd5\uff08\u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\/\u30bf\u30ad\u30b5\u30f3\uff09\u3078\u306e\u53cd\u5fdc\u6027\u304c\u4f4e\u304f\u3001\u5316\u5b66\u7642\u6cd5\u62b5\u6297\u6027<\/b>\u3092\u793a\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u6cbb\u7642\u304c\u6700\u3082\u96e3\u3057\u3044\u7279\u6b8a\u578b\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

            \u2464 \u30a2\u30dd\u30af\u30ea\u30f3\u764c\uff08Apocrine Carcinoma: AC\uff09<\/h4>\n
              \n
            • \n

              \u7279\u5fb4:<\/b> \u30a2\u30dd\u30af\u30ea\u30f3\u817a\uff08\u6c57\u817a\uff09\u306b\u985e\u4f3c\u3057\u305f\u5927\u304d\u306a\u597d\u9178\u6027\u306e\u7d30\u80de\u8cea\u3092\u6301\u3064\u7d30\u80de\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n<\/li>\n

            • \n

              TNBC\u3078\u306e\u5206\u985e:<\/b> \u591a\u304f\u306eAC\u306fER\u30fbPgR\u9670\u6027\u3067TNBC\u306b\u542b\u307e\u308c\u307e\u3059\u304c\u3001\u4e00\u90e8\u3001\u7279\u6b8a\u306a\u7537\u6027\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\uff08AR\uff09\u967d\u6027\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u793a\u3059\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/li>\n

            • \n

              \u6cbb\u7642\u3078\u306e\u5f71\u97ff:<\/b> TNBC\u3068\u3057\u3066\u306e\u6a19\u6e96\u6cbb\u7642\u306b\u6e96\u3058\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u304c\u3001AR\u967d\u6027\u3067\u3042\u308c\u3070\u5185\u5206\u6ccc\u7642\u6cd5\uff08\u6297\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u85ac\uff09\u304c\u691c\u8a0e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

              \n

              3. TNBC\u7279\u6b8a\u578b\u306b\u304a\u3051\u308b\u85ac\u7269\u7642\u6cd5\u306e\u5185\u5bb9<\/h2>\n

              TNBC\u306e\u85ac\u7269\u7642\u6cd5\u306f\u3001\u5316\u5b66\u7642\u6cd5\u3092\u4e3b\u8ef8\u3068\u3057\u3001\u8fd1\u5e74\u3067\u306f\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u3084PARP\u963b\u5bb3\u85ac\u3068\u3044\u3063\u305f\u65b0\u898f\u85ac\u5264\u304c\u65e9\u671f\u4e73\u764c\u306e\u8853\u524d\u30fb\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u52a0\u308f\u308a\u3001\u6a19\u6e96\u6cbb\u7642\u304c\u5927\u304d\u304f\u5909\u5316\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

              \u85ac\u7269\u7642\u6cd5\u306e\u9069\u7528\u306f\u3001\u7279\u6b8a\u578b\u304b\u5426\u304b<\/b>\u3068**\u75c5\u671f\u306e\u9032\u884c\u5ea6\uff08\u816b\u760d\u5f84\u3001\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u306e\u6709\u7121\uff09**\u306b\u3088\u3063\u3066\u5224\u65ad\u3055\u308c\u307e\u3059\u3002<\/p>\n

              3-1. \u4e88\u5f8c\u826f\u597d\u306a\u7279\u6b8a\u578b\uff08AdCC, SC, MC\uff09\u306e\u85ac\u7269\u7642\u6cd5<\/h3>\n

              \u4e88\u5f8c\u304c\u6975\u3081\u3066\u826f\u597d\u3067\u3042\u308b\u7279\u6b8a\u578b\u306b\u304a\u3044\u3066\u306f\u3001\u5316\u5b66\u7642\u6cd5\u306e\u9069\u5fdc\u306f\u975e\u5e38\u306b\u4f4e\u3044<\/b>\u3001\u3042\u308b\u3044\u306f\u4e0d\u8981<\/b>\u3068\u5224\u65ad\u3055\u308c\u307e\u3059\u3002<\/p>\n

                \n
              • \n

                \u817a\u69d8\u56a2\u80de\u764c\uff08AdCC\uff09\/ \u5206\u6ccc\u764c\uff08SC\uff09:<\/b><\/p>\n

                  \n
                • \n

                  \u57fa\u672c\u7684\u306b\u5316\u5b66\u7642\u6cd5\u306f\u63a8\u5968\u3055\u308c\u306a\u3044<\/b>\u3002\u5c40\u6240\u6cbb\u7642\uff08\u624b\u8853\u3068\u653e\u5c04\u7dda\u6cbb\u7642\uff09\u304c\u5b8c\u4e86\u3059\u308c\u3070\u3001\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u306f\u7d42\u4e86\u3068\u306a\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

                • \n

                  \u9ac4\u69d8\u764c\uff08MC\uff09:<\/b><\/p>\n

                    \n
                  • \n

                    \u53b3\u5bc6\u306aMC\u306e\u5b9a\u7fa9\u3092\u6e80\u305f\u3059\u5834\u5408\u306f\u3001\u4e88\u5f8c\u826f\u597d\u6027\u304b\u3089\u5316\u5b66\u7642\u6cd5\u3092\u7701\u7565\u3059\u308b\u691c\u8a0e\u304c\u306a\u3055\u308c\u307e\u3059\u304c\u3001IDC-NST\u306b\u8fd1\u3044\u975e\u5b9a\u578b\u7684\u306a\u5834\u5408\u306f\u3001\u901a\u5e38\u306eTNBC\u306e\u5316\u5b66\u7642\u6cd5\u306b\u6e96\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                    3-2. \u6a19\u6e96\u7684\u306aTNBC\uff08IDC-NST\u304a\u3088\u3073\u5316\u751f\u764c\u306a\u3069\uff09\u306e\u85ac\u7269\u7642\u6cd5<\/h3>\n

                    \u7279\u6b8a\u578b\u306e\u4e2d\u3067\u3082\u5316\u751f\u764c\u306a\u3069\u3001\u4e88\u5f8c\u304c\u4e0d\u826f\u3067\u3042\u308b\u304b\u3001\u901a\u5e38\u306eTNBC\u306b\u8fd1\u3044\u7d44\u7e54\u578b\u3068\u5224\u65ad\u3055\u308c\u308b\u5834\u5408\u306f\u3001\u4ee5\u4e0b\u306e\u6a19\u6e96\u7684\u306a\u6cbb\u7642\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n

                    \u2460 \u8853\u524d\u5316\u5b66\u7642\u6cd5\uff08\u30cd\u30aa\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u7642\u6cd5\uff09\u306e\u91cd\u8981\u6027<\/h4>\n

                    \u65e9\u671f\u4e73\u764c\u3067\u3042\u3063\u3066\u3082\u3001\u816b\u760d\u5f84\u304c\u5927\u304d\u3044\u5834\u5408\uff08T2\u4ee5\u4e0a\uff09\u3084\u3001\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u967d\u6027\u306e\u5834\u5408\u306b\u306f\u3001\u8853\u524d\u5316\u5b66\u7642\u6cd5<\/b>\u304c\u5f37\u304f\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n

                      \n
                    • \n

                      \u76ee\u7684:<\/b> \u816b\u760d\u3092\u5c0f\u3055\u304f\u3057\u3066\u5207\u9664\u53ef\u80fd\u306b\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u3092\u78ba\u8a8d\u3057\u3001**\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\uff08pCR\uff1a\u304c\u3093\u7d30\u80de\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3057\u305f\u72b6\u614b\uff09**\u3092\u76ee\u6307\u3059\u3053\u3068\u3067\u3059\u3002pCR\u304c\u5f97\u3089\u308c\u305f\u60a3\u8005\u3055\u3093\u306f\u3001\u8853\u5f8c\u4e88\u5f8c\u304c\u683c\u6bb5\u306b\u5411\u4e0a\u3057\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

                      \u2461 \u8853\u524d\u5316\u5b66\u7642\u6cd5\u306e\u6a19\u6e96\u30ec\u30b8\u30e1\u30f3<\/h4>\n

                      TNBC\u306e\u6a19\u6e96\u30ec\u30b8\u30e1\u30f3\u306f\u3001\u4e3b\u306b\u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u7cfb<\/b>\u3068\u30bf\u30ad\u30b5\u30f3\u7cfb<\/b>\u306e\u85ac\u5264\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n
                      \u85ac\u5264\u306e\u7a2e\u985e<\/strong><\/td>\n\u4ee3\u8868\u7684\u306a\u30ec\u30b8\u30e1\u30f3\u4f8b<\/strong><\/td>\n<\/tr>\n<\/thead>\n
                      \u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u7cfb<\/span><\/td>\n\u30a8\u30d4\u30eb\u30d3\u30b7\u30f3\uff08E\uff09\u3084\u30c9\u30ad\u30bd\u30eb\u30d3\u30b7\u30f3\uff08A\uff09\uff0b\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\uff08C\uff09<\/span><\/td>\n<\/tr>\n
                      \u30bf\u30ad\u30b5\u30f3\u7cfb<\/span><\/td>\n\u30c9\u30bb\u30bf\u30ad\u30bb\u30eb\uff08D\uff09\u3084\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\uff08T\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

                      \u7d44\u307f\u5408\u308f\u305b\u4f8b\u3068\u3057\u3066\u3001EC\u7642\u6cd5\u30924\u30b5\u30a4\u30af\u30eb\u884c\u3063\u305f\u5f8c\u306b\u3001\u30bf\u30ad\u30b5\u30f3\u7cfb\u85ac\u5264\uff08D\u307e\u305f\u306fT\uff09\u30924\u30b5\u30a4\u30af\u30eb\u884c\u3046EC-D<\/b>\u3084AC-T<\/b>\u306a\u3069\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u3002<\/p>\n

                      \u2462 \u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\uff08ICIs\uff09\u306e\u4f75\u7528<\/h4>\n

                      \u8fd1\u5e74\u3001TNBC\u6cbb\u7642\u306e\u6210\u7e3e\u3092\u5927\u304d\u304f\u5411\u4e0a\u3055\u305b\u3066\u3044\u308b\u306e\u304c\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u3067\u3059\u3002<\/p>\n

                        \n
                      • \n

                        \u85ac\u5264:<\/b> \u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\uff08\u5546\u54c1\u540d\uff1a\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0<\/b>\uff09<\/p>\n<\/li>\n

                      • \n

                        \u9069\u5fdc:<\/b> TNBC\u306e\u65e9\u671f\u4e73\u764c\u306b\u5bfe\u3057\u3001\u8853\u524d\u5316\u5b66\u7642\u6cd5\u3068\u4f75\u7528\u3057\u3066\u6295\u4e0e\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n

                      • \n

                        \u52b9\u679c:<\/b> \u5316\u5b66\u7642\u6cd5\u5358\u72ec\u306b\u6bd4\u3079\u3001pCR\u7387\u3092\u6709\u610f\u306b\u9ad8\u3081\u3001\u8853\u5f8c\u306e\u518d\u767a\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\uff08KEYNOTE-522\u8a66\u9a13\uff09\u3002<\/p>\n<\/li>\n<\/ul>\n

                        \u2463 \u8853\u5f8c\u306e\u6cbb\u7642\u6226\u7565\uff08Post-Neoadjuvant Therapy\uff09<\/h4>\n

                        \u8853\u524d\u5316\u5b66\u7642\u6cd5\u3092\u884c\u3063\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u304c\u3093\u7d30\u80de\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3057\u306a\u304b\u3063\u305f\uff08pCR\u975e\u9054\u6210\uff09\u60a3\u8005\u3055\u3093\u306b\u5bfe\u3057\u3066\u306f\u3001\u8853\u5f8c\u306b**\u3055\u3089\u306a\u308b\u88dc\u52a9\u7642\u6cd5\uff08\u5f37\u5316\u7642\u6cd5\uff09**\u304c\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002<\/p>\n

                          \n
                        • \n

                          \u30ab\u30da\u30b7\u30bf\u30d3\u30f3:<\/b> \u8853\u524d\u306b\u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\/\u30bf\u30ad\u30b5\u30f3\u7cfb\u6cbb\u7642\u3092\u53d7\u3051\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305apCR\u975e\u9054\u6210\u306e\u5834\u5408\u3001\u30ab\u30da\u30b7\u30bf\u30d3\u30f3\uff08\u30bc\u30ed\u30fc\u30c0\uff09\u306e\u5185\u670d\u304c\u6a19\u6e96\u7684\u306a\u5f37\u5316\u7642\u6cd5\u3067\u3059\u3002<\/p>\n<\/li>\n

                        • \n

                          \u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306e\u7d99\u7d9a:<\/b> \u8853\u524d\u304b\u3089\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3092\u6295\u4e0e\u3057\u3066\u3044\u305f\u5834\u5408\u3001\u8853\u5f8c\u3082\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

                          \u2464 BRCA\u5909\u7570\u967d\u6027\u8005\u3078\u306ePARP\u963b\u5bb3\u85ac<\/h4>\n

                          \u907a\u4f1d\u6027\u4e73\u764c\u5375\u5de3\u764c\uff08HBOC\uff09\u306e\u539f\u56e0\u907a\u4f1d\u5b50\u3067\u3042\u308bBRCA1\/2\u907a\u4f1d\u5b50\u5909\u7570<\/b>\u304c\u967d\u6027\u306e\u60a3\u8005\u3055\u3093\uff08TNBC\u3067\u9ad8\u983b\u5ea6\u306b\u898b\u3089\u308c\u308b\uff09\u306e\u5834\u5408\u3001\u7279\u5b9a\u306e\u85ac\u5264\u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n

                            \n
                          • \n

                            \u85ac\u5264:<\/b> \u30aa\u30e9\u30d1\u30ea\u30d6\uff08\u5546\u54c1\u540d\uff1a\u30ea\u30e0\u30d1\u30fc\u30b6<\/b>\uff09<\/p>\n<\/li>\n

                          • \n

                            \u9069\u5fdc:<\/b> \u8853\u524d\u306b\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u3001\u8853\u5f8c\u306b\u304c\u3093\u7d30\u80de\u304c\u6b8b\u5b58\u3057\u3066\u3044\u308b\uff08pCR\u975e\u9054\u6210\uff09BRCA\u5909\u7570\u967d\u6027\u8005\u306b\u5bfe\u3057\u3001\u30aa\u30e9\u30d1\u30ea\u30d6\u30921\u5e74\u9593\u5185\u670d\u3059\u308b\u3053\u3068\u3067\u3001\u518d\u767a\u30ea\u30b9\u30af\u3092\u6709\u610f\u306b\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08OlympiA\u8a66\u9a13\uff09\u3002<\/p>\n<\/li>\n<\/ul>\n

                            3-3. \u5316\u751f\u764c\uff08MpBC\uff09\u306e\u85ac\u7269\u7642\u6cd5\u3078\u306e\u6ce8\u610f\u70b9<\/h3>\n

                            \u5316\u751f\u764c\u306f\u524d\u8ff0\u306e\u901a\u308a\u3001\u901a\u5e38\u306eTNBC\u30ec\u30b8\u30e1\u30f3\uff08\u30a2\u30f3\u30b9\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\/\u30bf\u30ad\u30b5\u30f3\uff09\u306b\u5bfe\u3059\u308b\u53cd\u5fdc\u6027\u304c\u4f4e\u3044\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n

                              \n
                            • \n

                              \u4ee3\u66ff\u30ec\u30b8\u30e1\u30f3\u306e\u691c\u8a0e:<\/b> \u30d7\u30e9\u30c1\u30ca\u88fd\u5264\uff08\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u3001\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\uff09\u3084\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3\u3068\u3044\u3063\u305f\u3001\u901a\u5e38\u3068\u306f\u7570\u306a\u308b\u85ac\u5264\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30ec\u30b8\u30e1\u30f3\u304c\u691c\u8a0e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u6a19\u6e96\u6cbb\u7642\u3068\u3057\u3066\u306e\u78ba\u56fa\u305f\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u672a\u3060\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<\/li>\n

                            • \n

                              \u514d\u75ab\u7642\u6cd5\u306e\u671f\u5f85:<\/b> TNBC\u3067\u3042\u308b\u305f\u3081\u514d\u75ab\u7642\u6cd5\u306e\u9069\u5fdc\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u975e\u5b9a\u578b\u7684\u306a\u7d44\u7e54\u50cf\u3092\u6301\u3064\u305f\u3081\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u306b\u3088\u308a\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u306e\u78ba\u7acb\u304c\u5f85\u305f\u308c\u307e\u3059\u3002<\/p>\n<\/li>\n<\/ul>\n

                              \n

                              4. \u7d50\u8ad6\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/h2>\n

                              \u65e9\u671fTNBC\u306b\u304a\u3051\u308b\u7279\u6b8a\u578b\u306e\u8a3a\u65ad\u306f\u3001\u5316\u5b66\u7642\u6cd5\u3092\u56de\u907f\u3067\u304d\u308b\u53ef\u80fd\u6027<\/b>\uff08AdCC, SC\u306a\u3069\uff09\u3068\u3001\u6a19\u6e96\u5316\u5b66\u7642\u6cd5\u304c\u52b9\u304d\u306b\u304f\u3044\u53ef\u80fd\u6027<\/b>\uff08MpBC\uff09\u3092\u5224\u65ad\u3059\u308b\u4e0a\u3067\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n

                              \u7279\u306b\u3001\u5316\u5b66\u7642\u6cd5\u304c\u5fc5\u9808\u3068\u5224\u65ad\u3055\u308c\u308bTNBC\u306b\u304a\u3044\u3066\u306f\u3001\u8fd1\u5e74\u3001\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6<\/b>\u306e\u4f75\u7528\u3084\u3001BRCA\u5909\u7570\u967d\u6027\u8005\u3078\u306e\u30aa\u30e9\u30d1\u30ea\u30d6<\/b>\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u6cbb\u7642\u6210\u7e3e\u304c\u98db\u8e8d\u7684\u306b\u5411\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

                              TNBC\u306f\u6700\u3082\u500b\u5225\u5316\u6cbb\u7642\u304c\u9032\u3093\u3067\u3044\u308b\u9818\u57df\u306e\u4e00\u3064<\/b>\u3067\u3059\u3002\u3054\u81ea\u8eab\u306e\u7279\u6b8a\u578b\u304c\u3069\u306e\u5206\u985e\u306b\u5c5e\u3057\u3001\u307e\u305fBRCA\u5909\u7570\u306e\u6709\u7121\u306a\u3069\u3001\u8a73\u7d30\u306a\u691c\u67fb\u7d50\u679c\u306b\u57fa\u3065\u304d\u3001\u4e3b\u6cbb\u533b\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u6700\u9069\u306a\u6cbb\u7642\u6226\u7565\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"

                              \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\uff08Triple Negative Breast Cancer: TNBC\uff09\u30bf\u30a4\u30d7\u306e\u4e73\u764c\u306f\u3001\u4e73\u764c\u5168\u4f53\u306e\u7d0415\u301c20%\u3092\u5360\u3081\u308b\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3059\u3002\u3053\u306e\u30bf\u30a4\u30d7\u306f\u3001\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\uff08\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53 ER\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53 PgR\uff09\u304a\u3088\u3073\u30d2\u30c8\u4e0a\u76ae\u5897\u6b96\u56e0\u5b50\u53d7\u5bb9\u4f532\u578b\uff08HER2\uff09\u304c\u3059\u3079\u3066\u9670\u6027\u3067\u3042\u308b\u3068\u3044\u3046\u7279\u5fb4\u3092\u6301\u3061\u3001\u5185\u5206\u6ccc\u7642\u6cd5\u3084\u6297HER2\u7642\u6cd5\u304c\u52b9\u304b\u305a\u3001\u4e3b\u306b\u5316\u5b66\u7642\u6cd5\u304c\u6cbb\u7642\u306e\u4e3b\u8ef8\u3068\u306a\u308a\u307e\u3059\u3002 TNBC\u306e\u591a\u304f\u306f\u3001\u7279\u6b8a\u306a\u7d44\u7e54\u50cf\u3092\u6301\u305f\u306a\u3044\u6d78\u6f64\u6027\u4e73\u7ba1\u764c\u306e\u975e\u7279\u6b8a\u578b\uff08IDC-NST\uff09\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u304c\u3001\u4e00\u90e8\u306b\u306f\u4e88\u5f8c\u3084\u6cbb\u7642\u53cd\u5fdc\u6027\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u7279\u6b8a\u578b\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7279\u6b8a\u578b\u3092\u6b63\u78ba\u306b\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3001\u60a3\u8005\u3055\u3093\u306b\u3068\u3063\u3066\u9069\u5207\u306a\u6cbb\u7642\u6226\u7565\uff08\u7279\u306b\u5316\u5b66\u7642\u6cd5\u306e\u5f37\u5ea6\uff09\u3092\u9078\u629e\u3059\u308b\u305f\u3081\u306b\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002 \u672c\u7a3f\u3067\u306f\u3001\u65e9\u671f\u4e73\u764c\u306b\u304a\u3051\u308bTNBC\u306e\u7279\u6b8a\u578b\u306b\u7126\u70b9\u3092\u5f53\u3066\u3001\u305d\u306e\u75c5\u7406\u5b66\u7684\u7279\u5fb4\u3068\u3001\u5404\u7279\u6b8a\u578b\u304a\u3088\u3073\u6a19\u6e96TNBC\u306b\u5bfe\u3059\u308b\u85ac\u7269\u7642\u6cd5\u306e\u6700\u65b0\u306e\u5185\u5bb9\u306b\u3064\u3044\u3066\u3001\u8a73\u7d30\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002 1. \u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u764c\uff08TNBC\uff09\u306e\u6982\u8981 TNBC\u306f\u3001\u4ee5\u4e0b\u306e\u751f\u7269\u5b66\u7684\u7279\u5fb4\u3092\u6301\u3061\u307e\u3059\u3002 \u9ad8\u60aa\u6027\u5ea6: \u7d44\u7e54\u5b66\u7684\u60aa\u6027\u5ea6\uff08HG\uff09\u304c\u9ad8\u304f\u3001\u5897\u6b96\u306e\u6307\u6a19\u3067\u3042\u308bKi67\u304c\u9ad8\u7387\uff0860%\u4ee5\u4e0a\uff09\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044\u3002 \u4e88\u5f8c: \u6cbb\u7642\u3057\u306a\u3051\u308c\u3070\u4e88\u5f8c\u304c\u60aa\u3044\u304c\u3001\u5316\u5b66\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u65e9\u671f\u306b\u75c5\u7406\u5b66\u7684\u5b8c\u5168\u594f\u52b9\uff08pCR\uff09\u304c\u5f97\u3089\u308c\u305f\u5834\u5408\u306e\u4e88\u5f8c\u306f\u826f\u597d\u3002 \u518d\u767a\u30d1\u30bf\u30fc\u30f3: \u8a3a\u65ad\u5f8c5\u5e74\u4ee5\u5185\u306e\u65e9\u671f\u518d\u767a\u304c\u591a\u3044\u3002 \u5206\u5b50\u5b66\u7684\u7279\u5fb4: \u591a\u304f\u306eTNBC\u306f\u57fa\u5e95\u7d30\u80de\u69d8\uff08Basal-like\uff09\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u3092\u793a\u3057\u3001\u907a\u4f1d\u5b50\u5909\u7570\u4fee\u5fa9\u7d4c\u8def\u306b\u95a2\u308f\u308bBRCA1\/2\u907a\u4f1d\u5b50\u5909\u7570\u304c\u9ad8\u3044\u983b\u5ea6\u3067\u898b\u3089\u308c\u307e\u3059\u3002 2. TNBC\u306e\u7279\u6b8a\u578b\u3068\u305d\u306e\u75c5\u7406\u5b66\u7684\u7279\u5fb4 TNBC\u306b\u5206\u985e\u3055\u308c\u308b\u7279\u6b8a\u578b\u4e73\u764c\u306f\u3001\u5168\u4f53\u306e\u3054\u304f\u4e00\u90e8\u3067\u3059\u304c\u3001\u305d\u306e\u7d44\u7e54\u5b66\u7684\u7279\u5fb4\u304b\u3089\u3001\u901a\u5e38\u306eIDC-NST\u3068\u306f\u7570\u306a\u308b\u751f\u7269\u5b66\u7684\u7279\u6027\u3084\u4e88\u5f8c\u3092\u793a\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 2-1. \u4e88\u5f8c\u304c\u6bd4\u8f03\u7684\u826f\u597d\u306a\u7279\u6b8a\u578b \u3053\u308c\u3089\u306e\u7279\u6b8a\u578b\u306fTNBC\u306e\u5b9a\u7fa9\u3092\u6e80\u305f\u3059\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u975e\u7279\u6b8a\u578bTNBC\u306b\u6bd4\u3079\u3066\u4e88\u5f8c\u304c\u6975\u3081\u3066\u826f\u597d\u3067\u3042\u308b\u305f\u3081\u3001\u5316\u5b66\u7642\u6cd5\u306e\u9069\u5fdc\u304c\u614e\u91cd\u306b\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002 \u2460 \u817a\u69d8\u56a2\u80de\u764c\uff08Adenoid Cystic Carcinoma: AdCC\uff09 \u7279\u5fb4: \u975e\u5e38\u306b\u7a00\u306a\u30bf\u30a4\u30d7\u3067\u3001\u4e73\u817a\u5916\u306e\u553e\u6db2\u817a\u3084\u6c17\u7ba1\u652f\u817a\u306b\u3082\u767a\u751f\u3059\u308b\u816b\u760d\u3068\u7d44\u7e54\u50cf\u304c\u985e\u4f3c\u3057\u3066\u3044\u307e\u3059\u3002\u75c5\u7406\u5b66\u7684\u306b\u306f\u3001\u7be9\u72b6\u69cb\u9020\uff08\u3075\u308b\u3044\u306e\u3088\u3046\u306a\u69cb\u9020\uff09\u3084\u7ba1\u72b6\u30fb\u30fb\u30fb<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[15],"tags":[],"class_list":["post-647","post","type-post","status-publish","format-standard","hentry","category-15"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/647"}],"collection":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/comments?post=647"}],"version-history":[{"count":3,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/647\/revisions"}],"predecessor-version":[{"id":658,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/647\/revisions\/658"}],"wp:attachment":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/media?parent=647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/categories?post=647"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/tags?post=647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}