{"id":667,"date":"2026-01-01T09:39:26","date_gmt":"2026-01-01T00:39:26","guid":{"rendered":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/?p=667"},"modified":"2026-01-01T09:45:01","modified_gmt":"2026-01-01T00:45:01","slug":"%e4%b9%b3%e3%81%8c%e3%82%93%e8%a1%93%e5%be%8c%e3%81%ae%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3%e7%99%82%e6%b3%95%ef%bc%88%e8%a1%93%e5%be%8c%e8%a3%9c%e5%8a%a9%e5%86%85%e5%88%86%e6%b3%8c%e7%99%82%e6%b3%95","status":"publish","type":"post","link":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/%e8%96%ac%e7%89%a9%e7%99%82%e6%b3%95\/%e4%b9%b3%e3%81%8c%e3%82%93%e8%a1%93%e5%be%8c%e3%81%ae%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3%e7%99%82%e6%b3%95%ef%bc%88%e8%a1%93%e5%be%8c%e8%a3%9c%e5%8a%a9%e5%86%85%e5%88%86%e6%b3%8c%e7%99%82%e6%b3%95\/","title":{"rendered":"\u4e73\u304c\u3093\u8853\u5f8c\u306e\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\uff08\u8853\u5f8c\u88dc\u52a9\u5185\u5206\u6ccc\u7642\u6cd5\uff09\u306b\u3064\u3044\u3066"},"content":{"rendered":"<h3><strong>\u4e73\u304c\u3093\u8853\u5f8c\u306e\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\uff08\u8853\u5f8c\u88dc\u52a9\u5185\u5206\u6ccc\u7642\u6cd5\uff09\u306b\u3064\u3044\u3066<\/strong><\/h3>\n<h4><strong>1) <\/strong><strong>\u76ee\u7684\uff08\u306a\u305c\u3084\u308b\uff1f\uff09<\/strong><\/h4>\n<ul>\n<li>\u624b\u8853\u3067\u898b\u3048\u306a\u3044\u30ec\u30d9\u30eb\u306b\u6b8b\u3063\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3093\u7d30\u80de\u3092\u3001<strong>\u5973\u6027\u30db\u30eb\u30e2\u30f3\uff08\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\uff09\u523a\u6fc0\u304b\u3089\u9060\u3056\u3051\u3066\u518d\u767a\u3092\u6e1b\u3089\u3059<\/strong>\u6cbb\u7642\u3067\u3059\u3002<\/li>\n<li>\u52b9\u679c\u306f\u300c\u518d\u767a\u3092\u6e1b\u3089\u3059\u300d\u300c\u53cd\u5bfe\u5074\u306e\u4e73\u304c\u3093\u3092\u6e1b\u3089\u3059\u300d\u300c\uff08\u72b6\u6cc1\u306b\u3088\u3063\u3066\uff09\u751f\u5b58\u7387\u6539\u5584\u300d\u306b\u53ca\u3073\u307e\u3059\u3002<\/li>\n<\/ul>\n<h4><strong>2) <\/strong><strong>\u5bfe\u8c61\uff08\u8ab0\u306b\u52b9\u304f\uff1f\uff09<\/strong><\/h4>\n<ul>\n<li>\u539f\u5247\uff1a**ER\u967d\u6027\u307e\u305f\u306fPgR\u967d\u6027\uff08\uff1d\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\uff09**\u306e\u4e73\u304c\u3093\u3002<\/li>\n<li>\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u9670\u6027\uff08\u4f8b\uff1a\u591a\u304f\u306e\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\uff09\u3067\u306f\u3001\u901a\u5e38\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u306f\u884c\u3044\u307e\u305b\u3093\u3002<\/li>\n<\/ul>\n<h4><strong>3) <\/strong><strong>\u4f7f\u3046\u85ac\u306e\u7a2e\u985e\uff08\u4f55\u3092\u98f2\u3080\uff0f\u6253\u3064\uff1f\uff09<\/strong><\/h4>\n<ol>\n<li><strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff08SERM\uff09<\/strong><\/li>\n<\/ol>\n<ul>\n<li>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u85ac\u3002<strong>\u9589\u7d4c\u524d\u30fb\u9589\u7d4c\u5f8c\u3069\u3061\u3089\u3067\u3082<\/strong>\u4f7f\u3048\u307e\u3059\u3002<\/li>\n<li>\u9589\u7d4c\u524d\u306e\u6a19\u6e96\u7684\u9078\u629e\u80a2\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<ol>\n<li><strong>\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\uff08AI\uff09<\/strong><\/li>\n<\/ol>\n<ul>\n<li>\u4ee3\u8868\uff1a\u30a2\u30ca\u30b9\u30c8\u30ed\u30be\u30fc\u30eb\uff0f\u30ec\u30c8\u30ed\u30be\u30fc\u30eb\uff0f\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3\u7b49<\/li>\n<li><strong>\u9589\u7d4c\u5f8c\u3067\u7279\u306b\u63a8\u5968<\/strong>\u3055\u308c\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3088\u308a\u518d\u767a\u6291\u5236\u304c\u512a\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u305f\u3060\u3057\u526f\u4f5c\u7528\u306e\u6027\u8cea\u304c\u9055\u3046\uff09\u3002<\/li>\n<\/ul>\n<ol>\n<li><strong>\u5375\u5de3\u6a5f\u80fd\u6291\u5236\uff08OFS\uff1aLH-RH\u30a2\u30b4\u30cb\u30b9\u30c8\u7b49\uff09<\/strong><\/li>\n<\/ol>\n<ul>\n<li>\u6ce8\u5c04\u306a\u3069\u3067\u5375\u5de3\u306e\u50cd\u304d\u3092\u6291\u3048\u3001\u4f53\u5185\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3092\u4e0b\u3052\u307e\u3059\u3002<\/li>\n<li><strong>\u9589\u7d4c\u524d\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408<\/strong>\u306b\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3084AI\u306b\u4e0a\u4e57\u305b\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<h4><strong>4) <\/strong><strong>\u9589\u7d4c\u72b6\u6cc1\u5225\uff1a\u4ee3\u8868\u7684\u306a\u6cbb\u7642\u30d1\u30bf\u30fc\u30f3<\/strong><\/h4>\n<p><strong>\u9589\u7d4c\u524d\uff08\u307e\u305f\u306f\u9589\u7d4c\u306b\u8fd1\u3044\u6642\u671f\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u4f4e\u30ea\u30b9\u30af<\/strong>\uff1a\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5358\u72ec\uff08\u4e00\u822c\u306b5\u5e74\u304c\u57fa\u672c\uff09<\/li>\n<li><strong>\u4e2d\u301c\u9ad8\u30ea\u30b9\u30af<\/strong>\uff1a\n<ul>\n<li>OFS\uff0b\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3001\u307e\u305f\u306f<\/li>\n<li><strong>OFS<\/strong><strong>\uff0bAI<\/strong>\uff08\u3088\u308a\u5f37\u529b\u306b\u306a\u308a\u5f97\u308b\uff09<\/li>\n<\/ul>\n<\/li>\n<li>5\u5e74\u7d42\u4e86\u6642\u70b9\u3067\u9589\u7d4c\u5f8c\u306b\u306a\u3063\u3066\u3044\u308c\u3070\u3001AI\u3078\u5207\u308a\u66ff\u3048\u306a\u3069\u3092\u691c\u8a0e\u3059\u308b\u6d41\u308c\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>\u9589\u7d4c\u5f8c<\/strong><\/p>\n<ul>\n<li><strong>\u7b2c\u4e00\u9078\u629e\u3068\u3057\u3066AI\u304c\u5f37\u304f\u63a8\u5968<\/strong>\uff08\u526f\u4f5c\u7528\u306a\u3069\u3067\u96e3\u3057\u3044\u3068\u304d\u306f\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff09\u3002<\/li>\n<li>\u4f8b\uff09AI\u3092\u6700\u521d\u304b\u3089\u3001\u307e\u305f\u306f\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5f8c\u306bAI\u3078\u5207\u308a\u66ff\u3048\u3066\u5408\u8a085\u5e74\u3001\u306a\u3069\uff08\u8907\u6570\u30d1\u30bf\u30fc\u30f3\u304c\u3042\u308a\u307e\u3059\uff09\u3002<\/li>\n<\/ul>\n<h4><strong>5) <\/strong><strong>\u671f\u9593\uff1a5\u5e74\u304c\u57fa\u672c\u3001\u5fc5\u8981\u306b\u3088\u308a\u5ef6\u9577\uff087\u301c10\u5e74\u306a\u3069\uff09<\/strong><\/h4>\n<ul>\n<li>\u4ee5\u524d\u304b\u3089\u300c<strong>\u307e\u305a5\u5e74<\/strong>\u300d\u304c\u57fa\u672c\u3002<\/li>\n<li>\u518d\u767a\u30ea\u30b9\u30af\uff08\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3042\u308a\u3001\u816b\u760d\u304c\u5927\u304d\u3044\u3001\u60aa\u6027\u5ea6\u304c\u9ad8\u3044\u7b49\uff09\u3068\u526f\u4f5c\u7528\u30fb\u751f\u6d3b\u306e\u8cea\u3092\u898b\u306a\u304c\u3089\u3001**\u5ef6\u9577\uff08\u5408\u8a0810\u5e74\u306a\u3069\uff09**\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002\n<ul>\n<li>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u306f\u300c5\u5e74\u3088\u308a10\u5e74\u300d\u3067\u518d\u767a\u3084\u4e73\u304c\u3093\u6b7b\u3092\u3055\u3089\u306b\u6e1b\u3089\u3059\u30c7\u30fc\u30bf\u304c\u3042\u308a\u3001ASCO\u3067\u3082\u5ef6\u9577\u304c\u6271\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>AI\u306b\u3064\u3044\u3066\u3082\u3001\uff08\u3068\u304f\u306b\u9ad8\u30ea\u30b9\u30af\u3067\u306f\uff09\u5ef6\u9577\u7642\u6cd5\u304c\u8b70\u8ad6\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h4><strong>6) <\/strong><strong>\u4e3b\u306a\u526f\u4f5c\u7528\u3068\u30d5\u30a9\u30ed\u30fc\uff08\u304b\u306a\u308a\u5927\u4e8b\uff09<\/strong><\/h4>\n<p><strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3067\u591a\u3044\u3053\u3068<\/strong><\/p>\n<ul>\n<li>\u66f4\u5e74\u671f\u69d8\u75c7\u72b6\uff08\u307b\u3066\u308a\u3001\u6c17\u5206\u3001\u815f\u75c7\u72b6\u306a\u3069\uff09<\/li>\n<li>**\u8840\u6813\u75c7\uff08\u80ba\u585e\u6813\u306a\u3069\uff09**\u30ea\u30b9\u30af<\/li>\n<li><strong>\u5b50\u5bae\u5185\u819c\u304c\u3093<\/strong>\u30ea\u30b9\u30af\uff08\u7279\u306b\u9589\u7d4c\u5f8c\u3067\u6ce8\u610f\u3002\u51fa\u8840\u304c\u3042\u308c\u3070\u65e9\u3081\u306b\u53d7\u8a3a\uff09<\/li>\n<\/ul>\n<p><strong>AI<\/strong><strong>\u3067\u591a\u3044\u3053\u3068<\/strong><\/p>\n<ul>\n<li>\u95a2\u7bc0\u75db\u30fb\u3053\u308f\u3070\u308a<\/li>\n<li><strong>\u9aa8\u5bc6\u5ea6\u4f4e\u4e0b\uff0f\u9aa8\u6298\u30ea\u30b9\u30af\u5897\u52a0<\/strong>\uff08\u9aa8\u5bc6\u5ea6\u6e2c\u5b9a\u3001\u904b\u52d5\u3001Ca\/VitD\u3001\u5fc5\u8981\u306a\u3089\u9aa8\u7c97\u9b06\u75c7\u6cbb\u7642\u3092\u4f75\u7528\uff09<\/li>\n<li>\u815f\u4e7e\u71e5\u306a\u3069<\/li>\n<\/ul>\n<p><strong>OFS<\/strong><strong>\uff08\u5375\u5de3\u6291\u5236\uff09\u3067\u591a\u3044\u3053\u3068<\/strong><\/p>\n<ul>\n<li>\u5f37\u3044\u66f4\u5e74\u671f\u75c7\u72b6\u3001\u6027\u6a5f\u80fd\u30fb\u6c17\u5206\u3078\u306e\u5f71\u97ff\u3001\u9aa8\u5bc6\u5ea6\u4f4e\u4e0b\uff08AI\u4f75\u7528\u3060\u3068\u7279\u306b\u6ce8\u610f\uff09<\/li>\n<\/ul>\n<h4><strong>7) <\/strong><strong>\u3088\u304f\u3042\u308b\u5b9f\u52d9\u30dd\u30a4\u30f3\u30c8<\/strong><\/h4>\n<ul>\n<li><strong>\u98f2\u307f\u5fd8\u308c\u30fb\u4e2d\u65ad\u304c\u5897\u3048\u308b\u3068\u52b9\u679c\u304c\u843d\u3061\u3084\u3059\u3044<\/strong>\u305f\u3081\u3001\u526f\u4f5c\u7528\u306f\u6211\u6162\u305b\u305a\u65e9\u3081\u306b\u4e3b\u6cbb\u533b\u3078\uff08\u85ac\u306e\u5909\u66f4\u30fb\u5bfe\u7b56\u304c\u3044\u308d\u3044\u308d\u3042\u308a\u307e\u3059\uff09\u3002<\/li>\n<li>\u9589\u7d4c\u72b6\u614b\u306f\u6cbb\u7642\u4e2d\u306b\u5909\u308f\u308b\u3053\u3068\u304c\u3042\u308a\u3001<strong>\u6cbb\u7642\u9078\u629e\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u2194AI\uff09\u306b\u5f71\u97ff<\/strong>\u3057\u307e\u3059\u3002<\/li>\n<li>\u598a\u5a20\u671b\u30fb\u907f\u598a\u30fb\u66f4\u5e74\u671f\u75c7\u72b6\u30fb\u9aa8\u7c97\u9b06\u75c7\u30fb\u8840\u6813\u30ea\u30b9\u30af\u306a\u3069\u3001\u500b\u5225\u4e8b\u60c5\u3067\u6700\u9069\u89e3\u304c\u5909\u308f\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3><strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3<\/strong><\/h3>\n<p>\u4ee5\u4e0b\u306b**\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff08Tamoxifen\uff09**\u306e\u300c\u52b9\u679c\u30fb\u4f5c\u7528\u6a5f\u5e8f\u30fb\u526f\u4f5c\u7528\u300d\u3092\u3001\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u306e\u6587\u8108\u3067\u8981\u70b9\u6574\u7406\u3057\u307e\u3059\u3002<\/p>\n<p><strong>1) <\/strong><strong>\u52b9\u679c\uff08\u4f55\u306b\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<p><strong>\u4e73\u304c\u3093\uff08ER\u967d\u6027\uff0f\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\uff09\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u3067\u306e\u52b9\u679c<\/strong><\/p>\n<ul>\n<li><strong>\u518d\u767a\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b<\/strong>\uff08\u540c\u5074\u30fb\u9060\u9694\u518d\u767a\u306e\u4e21\u65b9\u3092\u542b\u3080\uff09<\/li>\n<li><strong>\u4e73\u304c\u3093\u6b7b\u4ea1\uff08\u4e73\u304c\u3093\u306b\u3088\u308b\u6b7b\u4ea1\uff09\u3092\u6e1b\u3089\u3059<\/strong><\/li>\n<li><strong>\u53cd\u5bfe\u5074\u306e\u4e73\u304c\u3093\uff08\u5bfe\u5074\u4e73\u304c\u3093\uff09\u767a\u751f\u3082\u6e1b\u3089\u3059<\/strong>\uff08\u4e88\u9632\u52b9\u679c\uff09<br \/>\n\u3053\u308c\u3089\u306f\u9577\u671f\u8ffd\u8de1\u8a66\u9a13\u3084\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u4e00\u8cab\u3057\u3066\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>\u671f\u9593\u306e\u8a71\uff085\u5e74\u2192\u5fc5\u8981\u306b\u3088\u308a10\u5e74\uff09<\/strong><\/p>\n<ul>\n<li>\u8853\u5f8c\u306b<strong>5\u5e74<\/strong>\u304c\u57fa\u672c\u3067\u3059\u304c\u3001\u30ea\u30b9\u30af\u306b\u3088\u3063\u3066\u306f<strong>10\u5e74\u307e\u3067\u5ef6\u9577<\/strong>\u3059\u308b\u3053\u3068\u3067\u3001ER\u967d\u6027\u3067\u306f<strong>\u518d\u767a\u30fb\u4e73\u304c\u3093\u6b7b\u4ea1\u304c\u3055\u3089\u306b\u4f4e\u4e0b<\/strong>\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>2) <\/strong><strong>\u4f5c\u7528\u6a5f\u5e8f\uff08\u3069\u3046\u3084\u3063\u3066\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<p><strong>SERM<\/strong><strong>\uff08\u9078\u629e\u7684\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u8abf\u7bc0\u85ac\uff09<\/strong><\/p>\n<ul>\n<li>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u306f<strong>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08ER\uff09\u306b\u7d50\u5408<\/strong>\u3057\u3001\u81d3\u5668\u306b\u3088\u3063\u3066 **\u300c\u6297\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u4f5c\u7528\u300d<strong>\u3068<\/strong>\u300c\u90e8\u5206\u7684\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u69d8\u4f5c\u7528\u300d**\u3092\u4f7f\u3044\u5206\u3051\u308b\u85ac\u3067\u3059\uff08\uff1dSERM\uff09\u3002<\/li>\n<\/ul>\n<p><strong>\u81d3\u5668\u3054\u3068\u306e\u4f5c\u7528\u306e\u30a4\u30e1\u30fc\u30b8<\/strong><\/p>\n<ul>\n<li><strong>\u4e73\u817a\uff08\u4e73\u304c\u3093\u7d30\u80de\uff09<\/strong>\uff1a\u4e3b\u306b<strong>\u6297\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u4f5c\u7528<\/strong> \u2192 ER\u3092\u4ecb\u3057\u305f\u5897\u6b96\u30b7\u30b0\u30ca\u30eb\u3092\u6291\u3048\u3066\u518d\u767a\u3092\u6e1b\u3089\u3059<\/li>\n<li><strong>\u5b50\u5bae\u5185\u819c<\/strong>\uff1a<strong>\u90e8\u5206\u7684\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u69d8\u4f5c\u7528<\/strong> \u2192 \u5185\u819c\u5897\u6b96\u304c\u8d77\u3053\u308a\u5f97\u308b\uff08\u3053\u308c\u304c\u5f8c\u8ff0\u306e\u5b50\u5bae\u4f53\u304c\u3093\u30ea\u30b9\u30af\u306b\u95a2\u9023\uff09<\/li>\n<li><strong>\u9aa8<\/strong>\uff1a\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u69d8\u4f5c\u7528\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u3001\uff08\u7279\u306b\u9589\u7d4c\u5f8c\u3067\u306f\uff09\u9aa8\u306b\u6709\u5229\u306b\u50cd\u304f\u5074\u9762\u304c\u3042\u308b<\/li>\n<li><strong>\u809d\u81d3<\/strong>\uff1a\u8102\u8cea\u3084\u51dd\u56fa\u56e0\u5b50\u3078\u306e\u5f71\u97ff\u3092\u901a\u3058\u3066\u8840\u6813\u30ea\u30b9\u30af\u306b\u95a2\u4fc2\u3057\u5f97\u308b<\/li>\n<\/ul>\n<p><strong>\u4ee3\u8b1d\uff08\u52b9\u304d\u76ee\u306b\u95a2\u4fc2\u3059\u308b\u30dd\u30a4\u30f3\u30c8\uff09<\/strong><\/p>\n<ul>\n<li>\u4f53\u5185\u3067\u4ee3\u8b1d\u3055\u308c\u3066\u6d3b\u6027\u4ee3\u8b1d\u7269\uff08\u4f8b\uff1aendoxifen \u306a\u3069\uff09\u304c\u52b9\u304d\u76ee\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002<br \/>\n\u305d\u306e\u305f\u3081\u3001**\u4e00\u90e8\u306e\u85ac\uff08CYP2D6\u3092\u5f37\u304f\u963b\u5bb3\u3059\u308b\u6297\u3046\u3064\u85ac\u306a\u3069\uff09**\u306f\u52b9\u679c\u3092\u5f31\u3081\u308b\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3001\u4f75\u7528\u85ac\u30c1\u30a7\u30c3\u30af\u304c\u91cd\u8981\u3067\u3059\uff08\u6dfb\u4ed8\u6587\u66f8\u3067\u3082\u76f8\u4e92\u4f5c\u7528\u3068\u3057\u3066\u6ce8\u610f\u559a\u8d77\u304c\u3042\u308a\u307e\u3059\uff09\u3002<\/li>\n<\/ul>\n<p><strong>3) <\/strong><strong>\u526f\u4f5c\u7528\uff08\u4f55\u306b\u6ce8\u610f\uff1f\uff09<\/strong><\/p>\n<p>\u526f\u4f5c\u7528\u306f\u300c\u3088\u304f\u3042\u308b\u3082\u306e\u300d\u3068\u300c\u307e\u308c\u3060\u304c\u91cd\u8981\u306a\u3082\u306e\u300d\u306b\u5206\u3051\u3066\u628a\u63e1\u3059\u308b\u3068\u5b9f\u7528\u7684\u3067\u3059\u3002<\/p>\n<p><strong>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528\uff08\u983b\u5ea6\u304c\u9ad8\u3044\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u307b\u3066\u308a\uff0f\u767a\u6c57<\/strong>\u306a\u3069\u306e\u66f4\u5e74\u671f\u69d8\u75c7\u72b6<\/li>\n<li><strong>\u815f\u5206\u6ccc\u7269\u5897\u52a0\u3001\u815f\u306e\u4e7e\u71e5\u30fb\u304b\u3086\u307f\u3001\u6027\u6a5f\u80fd\u306e\u5909\u5316<\/strong><\/li>\n<li><strong>\u6708\u7d4c\u4e0d\u9806\uff08\u9589\u7d4c\u524d\uff09<\/strong><\/li>\n<li>\u6c17\u5206\u5909\u52d5\u3001\u5026\u6020\u611f \u306a\u3069<br \/>\n\uff08\u3053\u3046\u3057\u305f\u75c7\u72b6\u306f\u201c\u3042\u308b\u7a0b\u5ea6\u306f\u8d77\u3053\u308a\u5f97\u308b\u201d\u524d\u63d0\u3067\u3001\u3064\u3089\u3051\u308c\u3070\u5bfe\u7b56\u3092\u7d44\u307f\u307e\u3059\uff09<\/li>\n<\/ul>\n<p><strong>\u91cd\u8981\u306a\u526f\u4f5c\u7528\uff08\u983b\u5ea6\u306f\u9ad8\u304f\u306a\u3044\u304c\u8981\u6ce8\u610f\uff09<\/strong><\/p>\n<p><strong>\u2460 <\/strong><strong>\u5b50\u5bae\u306e\u75c5\u5909\uff08\u5b50\u5bae\u4f53\u304c\u3093\u7b49\uff09<\/strong><\/p>\n<ul>\n<li>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u4f7f\u7528\u8005\u3067\u306f<strong>\u5b50\u5bae\u5185\u819c\u5897\u6b96\u301c\u5b50\u5bae\u4f53\u304c\u3093<\/strong>\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u308a\u5f97\u307e\u3059\u3002<\/li>\n<li>**\u4e0d\u6b63\u51fa\u8840\uff08\u9589\u7d4c\u5f8c\u51fa\u8840\u3001\u6708\u7d4c\u4ee5\u5916\u306e\u51fa\u8840\uff09**\u306f\u7279\u306b\u91cd\u8981\u306a\u30b5\u30a4\u30f3\u3067\u3001\u901f\u3084\u304b\u306a\u53d7\u8a3a\u30fb\u8a55\u4fa1\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>\u2461 <\/strong><strong>\u8840\u6813\u585e\u6813\u75c7\uff08DVT\/\u80ba\u585e\u6813\uff09\u30fb\u8133\u5352\u4e2d<\/strong><\/p>\n<ul>\n<li>**\u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\uff08DVT\uff09\uff0f\u80ba\u585e\u6813\uff08PE\uff09**\u306a\u3069\u306e\u8840\u6813\u30a4\u30d9\u30f3\u30c8\u304c\u5897\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u6dfb\u4ed8\u6587\u66f8\u306e\u67a0\u4ed8\u304d\u8b66\u544a\u3067\u3082\u5f37\u8abf\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>\u9577\u6642\u9593\u306e\u4e0d\u52d5\u3001\u624b\u8853\u3001\u80a5\u6e80\u3001\u55ab\u7159\u3001\u8840\u6813\u6b74\u306a\u3069\u304c\u3042\u308b\u5834\u5408\u306f\u7279\u306b\u6ce8\u610f\u3057\u3066\u4e3b\u6cbb\u533b\u3068\u76f8\u8ac7\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>\u2462 <\/strong><strong>\u767d\u5185\u969c<\/strong><\/p>\n<ul>\n<li>\u91cd\u5927\u526f\u4f5c\u7528\u3068\u3057\u3066<strong>\u767d\u5185\u969c<\/strong>\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u9577\u671f\u4f7f\u7528\u3067\u6ce8\u610f\uff09\u3002<\/li>\n<\/ul>\n<p>\uff08\u305d\u306e\u307b\u304b\u3001\u809d\u6a5f\u80fd\u7570\u5e38\u306a\u3069\u304c\u554f\u984c\u306b\u306a\u308b\u3053\u3068\u3082\u3042\u308b\u305f\u3081\u3001\u72b6\u6cc1\u306b\u3088\u308a\u63a1\u8840\u3067\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff09<\/p>\n<p><strong>4) <\/strong><strong>\u53d7\u8a3a\u306e\u76ee\u5b89\uff08\u5371\u967a\u30b5\u30a4\u30f3\uff09<\/strong><\/p>\n<p>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5185\u670d\u4e2d\u306b\u6b21\u304c\u3042\u308c\u3070\u3001\u65e9\u3081\u306b\u533b\u7642\u6a5f\u95a2\u3078\uff1a<\/p>\n<ul>\n<li><strong>\u4e0d\u6b63\u51fa\u8840<\/strong>\uff08\u9589\u7d4c\u5f8c\u51fa\u8840\u3001\u6708\u7d4c\u3068\u9055\u3046\u51fa\u8840\uff09<\/li>\n<li>\u7247\u811a\u306e\u816b\u308c\u30fb\u75db\u307f\u3001\u606f\u5207\u308c\u3001\u80f8\u75db\uff08\u8840\u6813\u306e\u30b5\u30a4\u30f3\uff09<\/li>\n<li>\u7247\u5074\u306e\u9ebb\u75fa\u3001\u8a00\u8449\u304c\u51fa\u306a\u3044\u3001\u6fc0\u3057\u3044\u982d\u75db\uff08\u8133\u5352\u4e2d\u306e\u30b5\u30a4\u30f3\uff09<\/li>\n<\/ul>\n<h3><strong>\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u963b\u5bb3\u5264<\/strong><\/h3>\n<p>\u4ee5\u4e0b\u306b**\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\uff08AI\uff1aanastrozole\uff0fletrozole\uff0fexemestane\uff09**\u306e\u300c\u52b9\u679c\u30fb\u4f5c\u7528\u6a5f\u5e8f\u30fb\u526f\u4f5c\u7528\u300d\u3092\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u306e\u6587\u8108\u3067\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n<p><strong>1) <\/strong><strong>\u52b9\u679c\uff08\u4f55\u306b\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<p><strong>\u5bfe\u8c61<\/strong><\/p>\n<ul>\n<li>\u57fa\u672c\u306f <strong>\u9589\u7d4c\u5f8c\u306e\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\uff08HR+\uff09\u65e9\u671f\u4e73\u304c\u3093<\/strong>\u306e\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u3002<\/li>\n<li><strong>\u9589\u7d4c\u524d<\/strong>\u3067\u306f\u3001\u539f\u5247 <strong>\u5375\u5de3\u6a5f\u80fd\u6291\u5236\uff08OFS\uff09\u3092\u4f75\u7528\u3057\u3066<\/strong>\u4f7f\u3046\uff08AI\u5358\u72ec\u306f\u4e0d\u5341\u5206\u306b\u306a\u308a\u5f97\u308b\u305f\u3081\uff09\u3002<\/li>\n<\/ul>\n<p><strong>\u671f\u5f85\u3067\u304d\u308b\u52b9\u679c\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3068\u306e\u6bd4\u8f03\u3092\u542b\u3080\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u518d\u767a\u3092\u3088\u308a\u6e1b\u3089\u3059<\/strong>\uff1aAI\u306f\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3088\u308a\u3001\u6cbb\u7642\u4e2d\u306e\u518d\u767a\u7387\u3092<strong>\u76f8\u5bfe\u7684\u306b\u7d0430%\u4f4e\u4e0b<\/strong>\u3055\u305b\u308b\uff08\u5927\u898f\u6a21\u30e1\u30bf\u89e3\u6790\uff09\u3002<\/li>\n<li><strong>\u4e73\u304c\u3093\u6b7b\u4ea1\u3092\u3055\u3089\u306b\u4f4e\u4e0b<\/strong>\uff1a5\u5e74AI\u306f\u30015\u5e74\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3068\u6bd4\u3079\u3066<strong>10\u5e74\u4e73\u304c\u3093\u6b7b\u4ea1\u3092\u7d0415%\u4f4e\u4e0b<\/strong>\u3055\u305b\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u30e1\u30bf\u89e3\u6790\uff09\u3002<\/li>\n<li><strong>\u5bfe\u5074\u4e73\u304c\u3093\u306e\u6291\u5236<\/strong>\u3082\u671f\u5f85\u3055\u308c\u307e\u3059\uff08\u5185\u5206\u6ccc\u7642\u6cd5\u5168\u822c\u306e\u52b9\u679c\u3068\u3057\u3066\uff09\u3002<\/li>\n<\/ul>\n<p><strong>\u671f\u9593\uff08\u3056\u3063\u304f\u308a\uff09<\/strong><\/p>\n<ul>\n<li>\u591a\u304f\u306e\u65b9\u306f<strong>\u5408\u8a085\u5e74<\/strong>\u3092\u57fa\u672c\u306b\u3001\u518d\u767a\u30ea\u30b9\u30af\u306b\u5fdc\u3058\u3066**\u5ef6\u9577\uff08\u7dcf\u6cbb\u7642\u671f\u9593\u306f\u6700\u592710\u5e74\u307e\u3067\uff09**\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>2) <\/strong><strong>\u4f5c\u7528\u6a5f\u5e8f\uff08\u3069\u3046\u3084\u3063\u3066\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u30a2\u30ed\u30de\u30bf\u30fc\u30bc<\/strong>\u306f\u3001\u8102\u80aa\u306a\u3069\u306e\u672b\u68a2\u7d44\u7e54\u3067 <strong>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u2192\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3<\/strong>\u3078\u306e\u5909\u63db\uff08\u6700\u7d42\u6bb5\u968e\uff09\u3092\u62c5\u3046\u9175\u7d20\u3067\u3059\u3002<\/li>\n<li>AI\u306f\u3053\u306e\u9175\u7d20\u3092\u963b\u5bb3\u3057\u3001<strong>\u9589\u7d4c\u5f8c\u306e\u4e3b\u8981\u306a\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u7523\u751f\u6e90\uff08\u672b\u68a2\u3067\u306e\u7523\u751f\uff09\u3092\u5f37\u529b\u306b\u4f4e\u4e0b<\/strong>\u3055\u305b\u3066\u3001<strong>ER\u967d\u6027\u4e73\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u523a\u6fc0\u3092\u65ad\u3064<\/strong>\u3053\u3068\u3067\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>\u85ac\u306e\u30bf\u30a4\u30d7<\/strong><\/p>\n<ul>\n<li><strong>\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\uff08\u53ef\u9006\u7684\u963b\u5bb3\uff09<\/strong>\uff1a\u30a2\u30ca\u30b9\u30c8\u30ed\u30be\u30fc\u30eb\u3001\u30ec\u30c8\u30ed\u30be\u30fc\u30eb<\/li>\n<li><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\uff08\u4e0d\u53ef\u9006\u7684\u963b\u5bb3\uff09<\/strong>\uff1a\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3<br \/>\n\uff08\u81e8\u5e8a\u7684\u306b\u306f\u201c\u3069\u308c\u3092\u4f7f\u3046\u304b\u201d\u3088\u308a\u3082\u300c\u526f\u4f5c\u7528\u3084\u7d99\u7d9a\u6027\u300d\u300c\u9aa8\u5bfe\u7b56\u300d\u306a\u3069\u304c\u91cd\u8981\u306b\u306a\u308a\u3084\u3059\u3044\u3067\u3059\uff09<\/li>\n<\/ul>\n<p><strong>3) <\/strong><strong>\u526f\u4f5c\u7528\uff08\u4f55\u306b\u6ce8\u610f\uff1f\uff09<\/strong><\/p>\n<p>AI\u306e\u526f\u4f5c\u7528\u306f\u300c<strong>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3092\u5f37\u304f\u4e0b\u3052\u308b<\/strong>\u300d\u3053\u3068\u306b\u7531\u6765\u3059\u308b\u3082\u306e\u304c\u4e2d\u5fc3\u3067\u3059\u3002<\/p>\n<p><strong>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/strong><\/p>\n<ul>\n<li><strong>\u95a2\u7bc0\u75db\u30fb\u3053\u308f\u3070\u308a\uff0f\u7b4b\u8089\u75db\uff08AI\u95a2\u9023\u7b4b\u9aa8\u683c\u75c7\u72b6\uff09<\/strong><\/li>\n<li><strong>\u307b\u3066\u308a\u3001\u5bdd\u6c57\u3001\u75b2\u52b4\u611f<\/strong>\u306a\u3069\u66f4\u5e74\u671f\u69d8\u75c7\u72b6<\/li>\n<li><strong>\u815f\u4e7e\u71e5\u30fb\u6027\u4ea4\u75db\u30fb\u5c3f\u8def\u75c7\u72b6<\/strong>\u306a\u3069\u6ccc\u5c3f\u751f\u6b96\u5668\u75c7\u72b6<\/li>\n<\/ul>\n<p><strong>\u91cd\u8981\u306a\u526f\u4f5c\u7528\uff08\u7279\u306b\u9aa8\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u9aa8\u5bc6\u5ea6\u4f4e\u4e0b\uff08\u9aa8\u7c97\u9b06\u75c7\uff09\uff0f\u9aa8\u6298\u30ea\u30b9\u30af\u5897\u52a0<\/strong>\n<ul>\n<li>\u4f8b\uff1aATAC\u8a66\u9a13\u3067\u306f\u30a2\u30ca\u30b9\u30c8\u30ed\u30be\u30fc\u30eb\u7fa4\u3067<strong>\u9aa8\u6298\u304c\u5897\u52a0<\/strong>\u3057\u305f\u3053\u3068\u304c\u6dfb\u4ed8\u6587\u66f8\u306b\u3082\u660e\u8a18\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>\u305d\u306e\u4ed6\u3001\u72b6\u6cc1\u306b\u3088\u308a\u6ce8\u610f<\/strong><\/p>\n<ul>\n<li><strong>\u8102\u8cea\uff08\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\u4e0a\u6607<\/strong>\u3084\u3001<strong>\u865a\u8840\u6027\u5fc3\u75be\u60a3\u304c\u3042\u308b\u4eba\u3067\u5fc3\u30a4\u30d9\u30f3\u30c8\u304c\u5897\u3048\u308b\u53ef\u80fd\u6027<\/strong>\u304c\u6307\u6458\u3055\u308c\u3001\u30ea\u30b9\u30af\u304c\u3042\u308b\u5834\u5408\u306f\u4e3b\u6cbb\u533b\u3068\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>4) <\/strong><strong>\u5b9f\u52d9\u3067\u5927\u4e8b\uff1a\u691c\u67fb\u30fb\u4e88\u9632\uff08\u9aa8\u5bfe\u7b56\u304c\u30ab\u30ae\uff09<\/strong><\/p>\n<ul>\n<li>AI\u958b\u59cb\u524d\u306b<strong>\u9aa8\u5bc6\u5ea6\uff08DEXA\uff09\u3092\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3<\/strong>\u3068\u3057\u3066\u6e2c\u308a\u3001\u6cbb\u7642\u4e2d\u3082\u5b9a\u671f\u7684\u306b\u30d5\u30a9\u30ed\u30fc\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>\u751f\u6d3b\u9762\uff1a<strong>\u8377\u91cd\u904b\u52d5\u3001\u8ee2\u5012\u4e88\u9632\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\uff0f\u30d3\u30bf\u30df\u30f3D<\/strong>\u306a\u3069\u3092\u57fa\u672c\u306b\u3001\u5fc5\u8981\u306a\u3089<strong>\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u3084\u30c7\u30ce\u30b9\u30de\u30d6<\/strong>\u3092\u4f75\u7528\u3057\u3066\u9aa8\u6298\u4e88\u9632\u3092\u56f3\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u5375\u5de3\u6a5f\u80fd\u6291\u5236\uff08OFS\uff1aLH-RH\u30a2\u30b4\u30cb\u30b9\u30c8\u7b49\uff09\uff1a\u30ea\u30e5\u30fc\u30d7\u30ea\u30f3\u3001\u30be\u30e9\u30c7\u30c3\u30af\u30b9<\/h3>\n<p>\u4ee5\u4e0b\u306b\u3001<strong>\u5375\u5de3\u6a5f\u80fd\u6291\u5236\uff08OFS\uff1aLH-RH\u3014GnRH\u3015\u30a2\u30b4\u30cb\u30b9\u30c8\uff09<\/strong>\u2014\u4ee3\u8868\u85ac <strong>\u30ea\u30e5\u30fc\u30d7\u30ea\u30f3\uff08\u30ea\u30e5\u30fc\u30d7\u30ed\u30ec\u30ea\u30f3\uff0fleuprolide\uff09<\/strong>\u3001<strong>\u30be\u30e9\u30c7\u30c3\u30af\u30b9\uff08\u30b4\u30bb\u30ec\u30ea\u30f3\uff0fgoserelin\uff09<\/strong>\u2014\u306e <strong>\u52b9\u679c\u30fb\u4f5c\u7528\u6a5f\u5e8f\u30fb\u526f\u4f5c\u7528<\/strong>\u3092\u3001\u4e73\u304c\u3093\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u306e\u6587\u8108\u3067\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n<p><strong>1) <\/strong><strong>\u52b9\u679c\uff08\u4f55\u306b\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<p><strong>\u5bfe\u8c61<\/strong><\/p>\n<ul>\n<li><strong>\u9589\u7d4c\u524d\u306e\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\uff08HR+\uff09\u4e73\u304c\u3093<\/strong>\u3067\u3001\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u306b\u4e0a\u4e57\u305b\u3055\u308c\u308b\u6cbb\u7642\u3067\u3059\u3002<br \/>\n\uff08\u7279\u306b\u300c\u5316\u5b66\u7642\u6cd5\u304c\u5fc5\u8981\u306a\u5c64\u300d\u300c\u82e5\u5e74\u300d\u306a\u3069\u3067\u6069\u6075\u304c\u5927\u304d\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff09<\/li>\n<\/ul>\n<p><strong>\u3069\u308c\u304f\u3089\u3044\u826f\u304f\u3059\u308b\uff1f<\/strong><\/p>\n<ul>\n<li>\u5927\u898f\u6a21\u8a66\u9a13\uff08SOFT\/TEXT\uff09\u3067\u306f\u3001<strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5358\u72ec<\/strong>\u306b\u6bd4\u3079\u3066 <strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff0bOFS<\/strong>\u306f\u7121\u518d\u767a\u95a2\u9023\u306e\u6210\u7e3e\u3092\u6539\u5584\u3057\u3001\u3055\u3089\u306b <strong>\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3\uff08AI\uff09\uff0bOFS<\/strong>\u306f <strong>\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff0bOFS<\/strong>\u3088\u308a <strong>DFS\uff08\u7121\u75c5\u751f\u5b58\uff09\u3084\u9060\u9694\u518d\u767a\u6307\u6a19<\/strong>\u3092\u6539\u5584\u3057\u307e\u3057\u305f\u3002<\/li>\n<li>\u3064\u307e\u308a\u5b9f\u52d9\u4e0a\u306f\n<ul>\n<li><strong>\u4e2d\u301c\u9ad8\u30ea\u30b9\u30af<\/strong>\uff1aOFS\u3092\u300c\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u300d\u307e\u305f\u306f\u300cAI\u300d\u306b<strong>\u4e0a\u4e57\u305b<\/strong><\/li>\n<li><strong>\u3088\u308a\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5c64<\/strong>\uff1a<strong>AI\uff0bOFS<\/strong>\u304c\u3088\u308a\u5f37\u529b\u306a\u9078\u629e\u80a2<br \/>\n\u3068\u3044\u3046\u4f4d\u7f6e\u3065\u3051\u3067\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>2) <\/strong><strong>\u4f5c\u7528\u6a5f\u5e8f\uff08\u3069\u3046\u3084\u3063\u3066\u52b9\u304f\uff1f\uff09<\/strong><\/p>\n<p><strong>GnRH<\/strong><strong>\u30a2\u30b4\u30cb\u30b9\u30c8\u306e\u201c\u30b9\u30a4\u30c3\u30c1\u3092\u5207\u308b\u201d\u4ed5\u7d44\u307f<\/strong><\/p>\n<ul>\n<li>\u30ea\u30e5\u30fc\u30d7\u30ea\u30f3\uff0f\u30be\u30e9\u30c7\u30c3\u30af\u30b9\u306f<strong>GnRH\uff08LH-RH\uff09\u30a2\u30b4\u30cb\u30b9\u30c8<\/strong>\u3067\u3059\u3002<\/li>\n<li>\u6295\u4e0e\u958b\u59cb\u76f4\u5f8c\u306f\u4e00\u6642\u7684\u306b <strong>LH\/FSH\u304c\u4e0a\u304c\u308b\uff08\u30d5\u30ec\u30a2\uff09\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u306e\u5f8c\u3001\u4e0b\u5782\u4f53\u306e\u53d7\u5bb9\u4f53\u304c\u6291\u3048\u8fbc\u307e\u308c\u3066 LH\/FSH\u304c\u4f4e\u4e0b\u3057\u3001\u7d50\u679c\u3068\u3057\u3066\u5375\u5de3\u304b\u3089\u306e\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u7523\u751f\u304c\u5f37\u304f\u6291\u5236<\/strong>\u3055\u308c\u307e\u3059\uff08\u85ac\u5264\u6027\u306e\u9589\u7d4c\u72b6\u614b\uff09\u3002<\/li>\n<li>\u591a\u304f\u306e\u5834\u5408\u3001<strong>\u85ac\u3092\u3084\u3081\u308b\u3068\u5375\u5de3\u6a5f\u80fd\u306f\u56de\u5fa9<\/strong>\u3057\u307e\u3059\uff08\u305f\u3060\u3057\u5e74\u9f62\u3084\u500b\u4eba\u5dee\u3042\u308a\uff09\u3002<\/li>\n<\/ul>\n<p><strong>AI<\/strong><strong>\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3068\u304d\u306e\u6ce8\u610f\uff08\u91cd\u8981\uff09<\/strong><\/p>\n<ul>\n<li>AI\u306f\u300c\u5375\u5de3\u304c\u6b62\u307e\u3063\u3066\u3044\u308b\u300d\u3053\u3068\u304c\u524d\u63d0\u306a\u306e\u3067\u3001**OFS\u304c\u4e0d\u5341\u5206\uff08\u5375\u5de3\u304c\u5b8c\u5168\u306b\u6291\u3048\u304d\u308c\u3066\u3044\u306a\u3044\uff09**\u3068\u52b9\u679c\u304c\u843d\u3061\u5f97\u307e\u3059\u3002<br \/>\n\u305d\u306e\u305f\u3081\u3001\u30ac\u30a4\u30c9\/\u5b9f\u52d9\u3067\u306f <strong>\u30a8\u30b9\u30c8\u30e9\u30b8\u30aa\u30fc\u30eb\u7b49\u3067\u6291\u5236\u3092\u78ba\u8a8d<\/strong>\u3059\u308b\u8003\u3048\u65b9\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><strong>3) <\/strong><strong>\u526f\u4f5c\u7528\uff08\u4f55\u306b\u6ce8\u610f\uff1f\uff09<\/strong><\/p>\n<p>\u526f\u4f5c\u7528\u306e\u4e2d\u5fc3\u306f\u300c<strong>\u4f4e\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u72b6\u614b\uff08\u65e9\u671f\u9589\u7d4c\u72b6\u614b\uff09<\/strong>\u300d\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n<p><strong>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/strong><\/p>\n<ul>\n<li><strong>\u307b\u3066\u308a\u30fb\u767a\u6c57<\/strong>\u3001\u306e\u307c\u305b\u3001\u4e0d\u7720<\/li>\n<li><strong>\u815f\u4e7e\u71e5\u30fb\u6027\u4ea4\u75db\u30fb\u6027\u6b32\u4f4e\u4e0b<\/strong>\u306a\u3069\u306e\u6027\u6a5f\u80fd\/\u6ccc\u5c3f\u751f\u6b96\u5668\u75c7\u72b6<\/li>\n<li><strong>\u6c17\u5206\u306e\u843d\u3061\u8fbc\u307f\u3001\u6c17\u5206\u5909\u52d5<\/strong>\uff08\u6291\u3046\u3064\u304c\u554f\u984c\u306b\u306a\u308b\u4eba\u3082\uff09<\/li>\n<li><strong>\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5fdc<\/strong>\uff08\u75db\u307f\u3001\u767a\u8d64\u3001\u5185\u51fa\u8840\u306a\u3069\uff09<\/li>\n<\/ul>\n<p><strong>\u91cd\u8981\u306a\u526f\u4f5c\u7528\uff08\u9577\u671f\u3067\u7279\u306b\u5927\u4e8b\uff09<\/strong><\/p>\n<ul>\n<li><strong>\u9aa8\u5bc6\u5ea6\u4f4e\u4e0b\uff08\u9aa8\u7c97\u9b06\u75c7\uff09\uff0f\u9aa8\u6298\u30ea\u30b9\u30af\u5897\u52a0<\/strong><br \/>\n\u2192 OFS\u306f\u9aa8\u306b\u4e0d\u5229\u306a\u306e\u3067\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u9aa8\u5bc6\u5ea6\u6e2c\u5b9a\uff08DEXA\uff09\u3084\u9aa8\u5bfe\u7b56\u3092\u7d44\u307f\u5408\u308f\u305b\u307e\u3059\u3002<\/li>\n<li><strong>\u4f53\u91cd\u5897\u52a0\u30fb\u4ee3\u8b1d\u5909\u5316\u3001\u8840\u4e2d\u8102\u8cea\u5909\u5316<\/strong>\u306a\u3069\u304c\u554f\u984c\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff08\u500b\u4eba\u5dee\uff09\u3002<\/li>\n<\/ul>\n<p><strong>\u307e\u308c\u3060\u304c\u77e5\u3063\u3066\u304a\u304d\u305f\u3044\u3053\u3068<\/strong><\/p>\n<ul>\n<li><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc<\/strong>\uff08\u606f\u82e6\u3057\u3055\u3001\u9854\u306e\u816b\u308c\u7b49\uff09\u306f\u7dca\u6025\u5bfe\u5fdc\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u201c<\/strong><strong>\u5375\u5de3\u6291\u5236\u306e\u629c\u3051\uff08ovarian escape\uff09\u201d<\/strong>\uff1a\u6ce8\u5c04\u3057\u3066\u3044\u3066\u3082\u6291\u5236\u304c\u4e0d\u5341\u5206\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u7279\u306bAI\u4f75\u7528\u3067\u306f\u8981\u6ce8\u610f\u3067\u3059\u3002<\/li>\n<\/ul>\n<p><strong>4) <\/strong><strong>\u5b9f\u52d9\u306e\u30dd\u30a4\u30f3\u30c8\uff08\u77ed\u304f\uff09<\/strong><\/p>\n<ul>\n<li><strong>OFS<\/strong><strong>\u306f\u5358\u72ec\u3088\u308a\u300c\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3 or AI\u300d\u306b\u4e0a\u4e57\u305b\u3057\u3066\u4f7f\u3046<\/strong>\u306e\u304c\u57fa\u672c\uff08\u4e73\u304c\u3093\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\uff09\u3002<\/li>\n<li><strong>AI<\/strong><strong>\uff0bOFS<\/strong>\u3092\u9078\u3076\u306a\u3089\u3001**\u5375\u5de3\u6291\u5236\u304c\u5341\u5206\u304b\uff08E2\u7b49\uff09**\u306e\u78ba\u8a8d\u304c\u3068\u3066\u3082\u91cd\u8981\u3002<\/li>\n<li>\u9aa8\uff1a<strong>\u9aa8\u5bc6\u5ea6\u30fb\u904b\u52d5\u30fbCa\/VitD\u30fb\u5fc5\u8981\u306a\u3089\u9aa8\u5438\u53ce\u6291\u5236\u85ac<\/strong>\u3092\u4e3b\u6cbb\u533b\u3068\u76f8\u8ac7\u3002<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u4e73\u304c\u3093\u8853\u5f8c\u306e\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\uff08\u8853\u5f8c\u88dc\u52a9\u5185\u5206\u6ccc\u7642\u6cd5\uff09\u306b\u3064\u3044\u3066 1) \u76ee\u7684\uff08\u306a\u305c\u3084\u308b\uff1f\uff09 \u624b\u8853\u3067\u898b\u3048\u306a\u3044\u30ec\u30d9\u30eb\u306b\u6b8b\u3063\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3093\u7d30\u80de\u3092\u3001\u5973\u6027\u30db\u30eb\u30e2\u30f3\uff08\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\uff09\u523a\u6fc0\u304b\u3089\u9060\u3056\u3051\u3066\u518d\u767a\u3092\u6e1b\u3089\u3059\u6cbb\u7642\u3067\u3059\u3002 \u52b9\u679c\u306f\u300c\u518d\u767a\u3092\u6e1b\u3089\u3059\u300d\u300c\u53cd\u5bfe\u5074\u306e\u4e73\u304c\u3093\u3092\u6e1b\u3089\u3059\u300d\u300c\uff08\u72b6\u6cc1\u306b\u3088\u3063\u3066\uff09\u751f\u5b58\u7387\u6539\u5584\u300d\u306b\u53ca\u3073\u307e\u3059\u3002 2) \u5bfe\u8c61\uff08\u8ab0\u306b\u52b9\u304f\uff1f\uff09 \u539f\u5247\uff1a**ER\u967d\u6027\u307e\u305f\u306fPgR\u967d\u6027\uff08\uff1d\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\uff09**\u306e\u4e73\u304c\u3093\u3002 \u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u9670\u6027\uff08\u4f8b\uff1a\u591a\u304f\u306e\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\uff09\u3067\u306f\u3001\u901a\u5e38\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u306f\u884c\u3044\u307e\u305b\u3093\u3002 3) \u4f7f\u3046\u85ac\u306e\u7a2e\u985e\uff08\u4f55\u3092\u98f2\u3080\uff0f\u6253\u3064\uff1f\uff09 \u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff08SERM\uff09 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u85ac\u3002\u9589\u7d4c\u524d\u30fb\u9589\u7d4c\u5f8c\u3069\u3061\u3089\u3067\u3082\u4f7f\u3048\u307e\u3059\u3002 \u9589\u7d4c\u524d\u306e\u6a19\u6e96\u7684\u9078\u629e\u80a2\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\uff08AI\uff09 \u4ee3\u8868\uff1a\u30a2\u30ca\u30b9\u30c8\u30ed\u30be\u30fc\u30eb\uff0f\u30ec\u30c8\u30ed\u30be\u30fc\u30eb\uff0f\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3\u7b49 \u9589\u7d4c\u5f8c\u3067\u7279\u306b\u63a8\u5968\u3055\u308c\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3088\u308a\u518d\u767a\u6291\u5236\u304c\u512a\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u305f\u3060\u3057\u526f\u4f5c\u7528\u306e\u6027\u8cea\u304c\u9055\u3046\uff09\u3002 \u5375\u5de3\u6a5f\u80fd\u6291\u5236\uff08OFS\uff1aLH-RH\u30a2\u30b4\u30cb\u30b9\u30c8\u7b49\uff09 \u6ce8\u5c04\u306a\u3069\u3067\u5375\u5de3\u306e\u50cd\u304d\u3092\u6291\u3048\u3001\u4f53\u5185\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3092\u4e0b\u3052\u307e\u3059\u3002 \u9589\u7d4c\u524d\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u306b\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3084AI\u306b\u4e0a\u4e57\u305b\u3057\u307e\u3059\u3002 4) \u9589\u7d4c\u72b6\u6cc1\u5225\uff1a\u4ee3\u8868\u7684\u306a\u6cbb\u7642\u30d1\u30bf\u30fc\u30f3 \u9589\u7d4c\u524d\uff08\u307e\u305f\u306f\u9589\u7d4c\u306b\u8fd1\u3044\u6642\u671f\uff09 \u4f4e\u30ea\u30b9\u30af\uff1a\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5358\u72ec\uff08\u4e00\u822c\u306b5\u5e74\u304c\u57fa\u672c\uff09 \u4e2d\u301c\u9ad8\u30ea\u30b9\u30af\uff1a OFS\uff0b\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3001\u307e\u305f\u306f OFS\uff0bAI\uff08\u3088\u308a\u5f37\u529b\u306b\u306a\u308a\u5f97\u308b\uff09 5\u5e74\u7d42\u4e86\u6642\u70b9\u3067\u9589\u7d4c\u5f8c\u306b\u306a\u3063\u3066\u3044\u308c\u3070\u3001AI\u3078\u5207\u308a\u66ff\u3048\u306a\u3069\u3092\u691c\u8a0e\u3059\u308b\u6d41\u308c\u304c\u3042\u308a\u307e\u3059\u3002 \u9589\u7d4c\u5f8c \u7b2c\u4e00\u9078\u629e\u3068\u3057\u3066AI\u304c\u5f37\u304f\u63a8\u5968\uff08\u526f\u4f5c\u7528\u306a\u3069\u3067\u96e3\u3057\u3044\u3068\u304d\u306f\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\uff09\u3002 \u4f8b\uff09AI\u3092\u6700\u521d\u304b\u3089\u3001\u307e\u305f\u306f\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u5f8c\u306bAI\u3078\u5207\u308a\u66ff\u3048\u3066\u5408\u8a085\u5e74\u3001\u306a\u3069\uff08\u8907\u6570\u30d1\u30bf\u30fc\u30f3\u304c\u3042\u308a\u307e\u3059\uff09\u3002 5) \u671f\u9593\uff1a5\u5e74\u304c\u57fa\u672c\u3001\u5fc5\u8981\u306b\u3088\u308a\u5ef6\u9577\uff087\u301c10\u5e74\u306a\u3069\uff09 \u4ee5\u524d\u304b\u3089\u300c\u307e\u305a5\u5e74\u300d\u304c\u57fa\u672c\u3002 \u518d\u767a\u30ea\u30b9\u30af\uff08\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3042\u308a\u3001\u816b\u760d\u304c\u5927\u304d\u3044\u3001\u60aa\u6027\u5ea6\u304c\u9ad8\u3044\u7b49\uff09\u3068\u526f\u4f5c\u7528\u30fb\u751f\u6d3b\u306e\u8cea\u3092\u898b\u306a\u304c\u3089\u3001**\u5ef6\u9577\uff08\u5408\u8a0810\u5e74\u306a\u3069\uff09**\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002 \u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u306f\u300c5\u5e74\u3088\u308a10\u5e74\u300d\u3067\u518d\u767a\u3084\u4e73\u304c\u3093\u6b7b\u3092\u3055\u3089\u306b\u6e1b\u3089\u3059\u30c7\u30fc\u30bf\u304c\u3042\u308a\u3001ASCO\u3067\u3082\u5ef6\u9577\u304c\u6271\u308f\u308c\u3066\u3044\u307e\u3059\u3002 AI\u306b\u3064\u3044\u3066\u3082\u3001\uff08\u3068\u304f\u306b\u9ad8\u30ea\u30b9\u30af\u3067\u306f\uff09\u5ef6\u9577\u7642\u6cd5\u304c\u8b70\u8ad6\u3055\u308c\u307e\u3059\u3002 6) \u4e3b\u306a\u526f\u4f5c\u7528\u3068\u30d5\u30a9\u30ed\u30fc\uff08\u304b\u306a\u308a\u5927\u4e8b\uff09 \u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3067\u591a\u3044\u3053\u3068 \u66f4\u5e74\u671f\u69d8\u75c7\u30fb\u30fb\u30fb<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13],"tags":[51],"class_list":["post-667","post","type-post","status-publish","format-standard","hentry","category-13","tag-51"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/667"}],"collection":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/comments?post=667"}],"version-history":[{"count":3,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/667\/revisions"}],"predecessor-version":[{"id":670,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/posts\/667\/revisions\/670"}],"wp:attachment":[{"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/media?parent=667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/categories?post=667"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tokyo-breast-clinic.jp\/seminar\/wp-json\/wp\/v2\/tags?post=667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}